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Post-puncture headache, back pain or low-grade fever can occur for 1-3 days.","preparation":["Neurology review of diagnosis and stage","Baseline MMSE or MoCA testing","Brain MRI or CT review","Blood tests and infection screening","Review and adjust anticoagulants","Medication list reviewed","Caregiver or legal guardian consent"],"recovery_timeline":[{"phase":"Day 0-1","description":"Cell administration followed by observation for reactions, headache or fever.","restrictions":["Lie flat if intrathecal","Avoid driving","Stay hydrated"]},{"phase":"Days 2-7","description":"Mild fatigue or headache may settle; monitoring of neurological status continues.","restrictions":["No strenuous activity","Caregiver supervision"]},{"phase":"Weeks 2-4","description":"Return to normal routine; early follow-up checks.","restrictions":["Report fever, severe headache or new neurological symptoms"]},{"phase":"Months 3-6","description":"Cognitive reassessment to evaluate any change.","restrictions":[]}],"rehabilitation_days":{"min":3,"max":7,"unit":"days","qualifier":"Time to ordinary function after administration; cognitive rehabilitation, if used, continues separately."},"result_longevity":"No proven benefit or durability has been established. Any reported effect in trials is variable and often transient, with some clinics repeating courses after 3-6 months.","revision_rate_pct":{"min":0,"max":0,"unit":"percent","qualifier":"No corrective revision is typical; repeat dosing is counted under sessions or stages."},"scars":"No visible scar; only a small needle puncture mark at the lumbar or IV site. If cells are harvested by liposuction or marrow aspiration, a tiny puncture mark remains.","sessions_or_stages":{"sessions":{"min":1,"max":3,"unit":"visits","qualifier":"Usually one course of IV or intrathecal doses in one stay; some clinics repeat after 3-6 months."},"stages":[{"code":"assessment_screening","label":"Assessment and screening","after":{"min":0,"max":0,"unit":"days","qualifier":"Done on arrival before treatment."}},{"code":"cell_administration","label":"IV or intrathecal cell administration","after":{"min":1,"max":3,"unit":"days","qualifier":"Doses given within one stay."}},{"code":"repeat_course","label":"Optional repeat course","after":{"min":90,"max":180,"unit":"days","qualifier":"Only if the clinic protocol repeats dosing."}}],"qualifier":"Typical protocol is one course within a single stay."},"success":{"metric":null,"value":null,"unit":null,"horizon":null,"population":"Adults with mild Alzheimer's or mild cognitive impairment in small early-phase trials","evidence_status":"not_proven"},"techniques":[{"name":"Intravenous mesenchymal stem cell infusion","suits_whom":"Early-stage or mild cognitive impairment patients preferring a less invasive route.","recovery":"Same-day discharge; mild fever or fatigue for 1-2 days."},{"name":"Intrathecal stem cell injection","suits_whom":"Patients in trials seeking direct delivery to cerebrospinal fluid.","recovery":"Rest 24 hours; possible headache for 1-3 days."},{"name":"Intranasal stem cell delivery","suits_whom":"Experimental option for mild disease avoiding needles.","recovery":"No downtime; minimal local irritation."}],"treatment_conditions":["outpatient"],"treatment_duration_hours":{"min":2,"max":6,"unit":"hours","qualifier":"Infusion or lumbar puncture plus several hours of post-dose observation per session."},"initial_assessment_documents":["Neurologist report with Alzheimer's diagnosis","Brain MRI or CT report","MMSE or MoCA cognitive test results","Amyloid or tau PET report (if 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adequately studied under an IND to demonstrate the claims of safety and effectiveness.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"F4","text":"The provider asks you to sign before explaining the process and known risks","scope":"treatment_type","source":{"url":"https://www.fda.gov/safety/medical-product-safety-information/public-safety-alert-due-marketing-unapproved-stem-cell-and-exosome-products","host":"fda.gov","quote":"Make sure you understand the entire process and known risks before you sign.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}}],"checked_at":"2026-11-13","next_check_at":"2027-11-13","version":1},"warning_signs":{"status":"missing","reason":"no_official_source","checked_at":"2026-11-13","next_check_at":"2027-02-11"},"take_home":{"status":"ok","items":[{"id":"T1","text":"Home doctor needs the clinic's follow-up recommendations in a written discharge summary","document":"discharge 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