{"key":"op_1484_MX","page":{"url":"https://pt.bookimed.com/clinics/country=mexico/procedure=stem-cell-for-ankylosing-spondylitis/","procedure":{"id":1484,"slug":"stem-cell-for-ankylosing-spondylitis","name":"Terapia com células estaminais para espondilite anquilosante","name_forms":{"plural":{"status":"missing","reason":"not_collected"},"genitive":{"status":"missing","reason":"not_collected"}},"type":"therapy","grammar_number":{"status":"missing","reason":"not_collected"},"parent_id":"stem-cells","family_attribute":{"status":"missing","reason":"not_collected"}},"country":{"id":40,"iso":"MX","name":"México"},"currency":"USD","data_date":"2026-06-09"},"pages":{"clinics_url":"https://pt.bookimed.com/clinics/country=mexico/procedure=stem-cell-for-ankylosing-spondylitis/","cost_url":"https://pt.bookimed.com/clinics/country=mexico/procedure=stem-cell-for-ankylosing-spondylitis/cost/","best_url":{"status":"missing","reason":"template not live"}},"price":{"from":3000,"to":13500,"avg":{"value":3000,"method":"median","source":"clinics"},"us":{"from":8000,"to":14000},"uk":{"from":9500,"to":25000},"by_technique":{"status":"missing","reason":"not_collected"},"by_city":[{"city":"Guadalajara","from":3000},{"city":"Monterrei","from":3000},{"city":"Playa del Carmen","from":8500},{"city":"Mexicali","from":6500},{"city":"Cidade do México","from":6500},{"city":"Cancún","from":6500}],"per_unit":{"status":"missing","reason":"not_collected"},"factors":["Board-certified specialists with 15+ years of experience can charge 25%–35% more for their expertise.","Clinics accredited by JCI or ISO 9001 quality systems may charge 15%–20% more for meeting international safety protocols.","Procedures in major cities like Mexico City or Guadalajara can cost 20%–30% more due to high-demand urban hospitals.","Source of stem cells (autologous vs allogeneic) can affect cost by 15%–25%, with autologous extractions typically higher.","Use of ISO-certified cell processing labs can add 10%–15% to ensure cell purity and viability for therapy.","Number of stem cell infusions required can increase total cost by $2,000–$4,000 per additional session."],"tiers":{"status":"missing","reason":"no_offers"},"comparison":[{"country_iso":"UA","from":9900,"to":12500},{"country_iso":"FR","from":14000,"to":25000},{"country_iso":"GB","from":9500,"to":25000},{"country_iso":"US","from":8000,"to":14000},{"country_iso":"IL","from":14000,"to":23000},{"country_iso":"TR","from":6500,"to":11000},{"country_iso":"DE","from":8500,"to":15000},{"country_iso":"CA","from":9500,"to":19000},{"country_iso":"AE","from":9500,"to":20000},{"country_iso":"TH","from":19600,"to":{"status":"missing","reason":"not_collected"}},{"country_iso":"PL","from":5500,"to":10000},{"country_iso":"KR","from":8000,"to":16000},{"country_iso":"CZ","from":5500,"to":9500},{"country_iso":"AT","from":9500,"to":18000},{"country_iso":"ES","from":6500,"to":12500},{"country_iso":"IT","from":7500,"to":15000},{"country_iso":"CN","from":14000,"to":28000},{"country_iso":"AU","from":9000,"to":19000},{"country_iso":"IN","from":6500,"to":11000},{"country_iso":"MY","from":9000,"to":16000},{"country_iso":"VN","from":7500,"to":12500},{"country_iso":"BR","from":9000,"to":18000},{"country_iso":"CO","from":5500,"to":11000}],"base_country":"US","base_is_fallback":false},"savings":{"pct":63,"variant":"ranges_overlap"},"package":{"included":{"status":"missing","reason":"no_offers"},"excluded":{"status":"missing","reason":"no_offers"},"extra_charges":{"status":"missing","reason":"not_collected"}},"clinics":{"count":5,"items":[{"id":8068,"name":"CellsClinic","city":"Monterrey","rating":{"status":"missing","reason":"not_collected"},"reviews_count":{"status":"missing","reason":"not_collected"},"accreditations":{"status":"missing","reason":"not_collected"},"rank":1,"has_procedure":true,"why_ranked":"Uses mesenchymal stem cells for immunomodulation, achieving 85% reduction in disease flares. COFEPRIS-authorized with in-house certified cell lab.","bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}},{"id":3702,"name":"Immunotherapy Regenerative Medicine","city":"Puerto Vallarta","rating":5,"reviews_count":4,"accreditations":["Consejo de Salubridad General"],"rank":2,"has_procedure":true,"why_ranked":"Specializes in regenerative medicine with 15+ years of research. Offers personalized stem cell treatments for ankylosing spondylitis. Multidisciplinary team includes biologists and biochemists.","bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}},{"id":6331,"name":"Giostar Stem Cell Therapy | Playa del Carmen Clinic","city":"Playa del Carmen","rating":{"status":"missing","reason":"not_collected"},"reviews_count":{"status":"missing","reason":"not_collected"},"accreditations":{"status":"missing","reason":"not_collected"},"rank":3,"has_procedure":true,"why_ranked":{"status":"missing","reason":"not_collected"},"bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}},{"id":6332,"name":"Giostar Stem Cell Therapy | Los Algodones Clinic","city":"Playa del Carmen","rating":{"status":"missing","reason":"not_collected"},"reviews_count":{"status":"missing","reason":"not_collected"},"accreditations":{"status":"missing","reason":"not_collected"},"rank":4,"has_procedure":true,"why_ranked":{"status":"missing","reason":"not_collected"},"bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}},{"id":7370,"name":"Dr. Irwin Abad Medicina Estética y Regenerativa","city":"Guadalajara","rating":{"status":"missing","reason":"not_collected"},"reviews_count":{"status":"missing","reason":"not_collected"},"accreditations":["International Society for Stem Cell Application"],"rank":5,"has_procedure":true,"why_ranked":{"status":"missing","reason":"not_collected"},"bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}}]},"doctors":{"count":4,"languages":{"status":"missing","reason":"not_collected"}},"cities":[{"id":397,"slug":"guadalajara","name":"Guadalajara","clinics_count":1,"price_from":3000,"profile":{"city_type":"Capital of Jalisco state, Mexico","access":["Guadalajara Airport (GDL), 17 km from downtown"],"sources":["https://en.wikipedia.org/wiki/Guadalajara","https://en.wikipedia.org/wiki/Guadalajara_International_Airport"],"checked_at":"2026-11-03","status":"ok"}},{"id":440,"slug":"monterrey","name":"Monterrei","clinics_count":2,"price_from":3000,"profile":{"city_type":"Capital of Nuevo León, Mexico","access":["Monterrey Airport (MTY), 28 km from downtown"],"sources":["https://en.wikipedia.org/wiki/Monterrey","https://en.wikipedia.org/wiki/Monterrey_International_Airport"],"checked_at":"2026-11-03","status":"ok"}},{"id":391,"slug":"playa-del-carmen","name":"Playa del Carmen","clinics_count":{"status":"missing","reason":"not_collected"},"price_from":8500,"profile":{"city_type":"Caribbean resort city in Mexico","access":["Cancun Airport (CUN), 70 km from Playa del Carmen"],"sources":["https://en.wikipedia.org/wiki/Playa_del_Carmen"],"checked_at":"2026-11-03","status":"ok"}},{"id":437,"slug":"mexicali","name":"Mexicali","clinics_count":{"status":"missing","reason":"not_collected"},"price_from":6500,"profile":{"city_type":"Border city opposite Calexico, California","access":["Calexico crossing, about five minute walk into Mexicali","Mexicali Airport (MXL), 20 km east of the city"],"sources":["https://en.wikipedia.org/wiki/Mexicali","https://en.wikivoyage.org/wiki/Mexicali"],"checked_at":"2026-11-03","status":"ok"}},{"id":423,"slug":"mexico-city","name":"Cidade do México","clinics_count":{"status":"missing","reason":"not_collected"},"price_from":6500,"profile":{"city_type":"Capital and largest city of Mexico","access":["Mexico City Airport (MEX), 5 km east of downtown"],"sources":["https://en.wikipedia.org/wiki/Mexico_City","https://en.wikipedia.org/wiki/Mexico_City_International_Airport"],"checked_at":"2026-11-03","status":"ok"}},{"id":454,"slug":"cancun","name":"Cancún","clinics_count":{"status":"missing","reason":"not_collected"},"price_from":6500,"profile":{"city_type":"Planned Mexican tourist destination city","access":["Cancún Airport (CUN), under 10 km from the Hotel Zone"],"sources":["https://en.wikipedia.org/wiki/Cancún","https://en.wikipedia.org/wiki/Cancún_International_Airport"],"checked_at":"2026-11-03","status":"ok"}}],"offers":{"active":{"status":"missing","reason":"no_offers"},"active_with_related":{"status":"missing","reason":"no_offers"},"hospital_nights_median":{"status":"missing","reason":"no_offers"},"days_in_country_median":{"status":"missing","reason":"no_offers"},"top_offers":{"status":"missing","reason":"no_offers"},"packages":{"status":"missing","reason":"no_offers"},"related_packages":{"status":"missing","reason":"no_offers"},"other_packages":{"status":"missing","reason":"no_offers"}},"medical":{"indications":["Active ankylosing spondylitis refractory to NSAIDs"],"contraindications":["Active infection","Current or past malignancy","Pregnancy or breastfeeding","Severe cardiac, renal or hepatic disease","Bleeding disorder or anticoagulant use","Uncontrolled immunosuppression or HIV","Allergy to anesthetic or product components"],"operation_hours":{"min":2,"max":4,"unit":"hours","qualifier":"2-4 hours per visit; harvest or infusion, excluding weeks of cell culture."},"anesthesia":["local"],"sessions_or_stages":{"sessions":{"min":1,"max":2,"unit":"visits","qualifier":"Two visits for autologous cells; allogeneic product needs one."},"stages":[{"code":"harvest","label":"Cell harvest from bone marrow or fat","after":{"min":0,"max":0,"unit":"days","qualifier":"Day of treatment"}},{"code":"infusion","label":"Intravenous stem cell infusion","after":{"min":14,"max":28,"unit":"days","qualifier":"After 2-4 weeks of cell culture"}}],"qualifier":"Autologous cells are expanded in culture between harvest and infusion."},"hospital_nights":{"value":{"min":16,"max":33,"unit":"nights","qualifier":"16-33 nights: harvest, 2-4 week culture wait, infusion, post-infusion check."},"source":"parsed_details"},"treatment_conditions":["day_case"],"rehabilitation_days":{"min":3,"max":7,"unit":"days","qualifier":"Ordinary functional recovery after harvest and infusion; physiotherapy for spondylitis continues separately."},"fly_home_after_days":{"min":2,"max":5,"unit":"days","qualifier":"After post-infusion check and resolution of fever or harvest site pain."},"back_to_work_days":{"min":1,"max":3,"unit":"days","qualifier":"Depends on harvest site discomfort and infusion reaction; desk work resumes sooner than physical work."},"exercise_resume_weeks":{"min":1,"max":2,"unit":"weeks","qualifier":"Light activity first; harvest site healing and infusion tolerance determine return to full exercise."},"final_result_months":{"min":3,"max":6,"unit":"months","qualifier":"Any effect on symptoms is gradual and unproven; assessed by disease activity scores."},"result_longevity":"Not established; durability of any symptomatic benefit is unproven.","main_risks":["Infection, infusion reactions, bleeding or harvest-site pain.","Unknown long-term safety of stem cell products."],"complication_rate_pct":{"min":10,"max":30,"unit":"percent","qualifier":"Mostly mild transient events (fever, headache, harvest site pain) within 30 days; serious events rare."},"revision_rate_pct":{"status":"missing","reason":"not_collected"},"success":{"metric":{"status":"missing","reason":"not_collected"},"value":{"status":"missing","reason":"not_collected"},"horizon":{"status":"missing","reason":"not_collected"},"source":{"status":"missing","reason":"not_collected"},"evidence_status":"not_proven"},"scars":"No visible scar; a small needle puncture mark at the harvest site fades within days.","pain":"Mild discomfort at the harvest site and cannula insertion; infusion itself is usually painless. Transient low-grade fever or headache can occur.","preparation":["Rheumatologist review of diagnosis and disease activity","Blood tests including CRP, ESR, infection screening","Recent pelvis and sacroiliac MRI","Review and adjust biologic and NSAID therapy","Stop blood thinners as advised","Fasting only if sedation is used"],"recovery_timeline":[{"phase":"Day 0 (harvest)","description":"Bone marrow or fat harvest under local anesthesia; cells sent for culture.","restrictions":["No driving after procedure","Rest for the day"]},{"phase":"Days 1-7 after harvest","description":"Mild harvest site soreness, possible transient fever or fatigue; return to light daily activity.","restrictions":["Avoid heavy lifting","Keep harvest site clean and dry"]},{"phase":"Weeks 1-4 culture wait","description":"Patient remains near clinic or returns home while cells are expanded.","restrictions":["Continue prescribed physiotherapy","Report fever or infection signs"]},{"phase":"Infusion day (about weeks 2-4)","description":"Intravenous cell infusion with observation for reactions.","restrictions":["No driving after infusion","Rest for the day"]},{"phase":"Weeks 1-12 after infusion","description":"Resume normal exercise and physiotherapy; gradual symptom assessment.","restrictions":["Report fever or infection signs"]},{"phase":"Months 3-6","description":"Evaluation of response and disease activity.","restrictions":{"status":"missing","reason":"not_collected"}}],"follow_up_visits":[{"purpose":"wound_check","requirement":"routine","after":{"min":2,"max":7,"unit":"days","qualifier":"Harvest site check in clinic before infusion."}},{"purpose":"assessment","requirement":"routine","after":{"min":30,"max":90,"unit":"days","qualifier":"Disease activity review with CRP, ESR and symptom scores."}},{"purpose":"result_review","requirement":"routine","after":{"min":90,"max":180,"unit":"days","qualifier":"Response evaluation with rheumatologist, may include repeat MRI."}}],"sources":{"status":"missing","reason":"not_collected"},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Confirm the surgeon is trained and experienced in the exact procedure you are considering, not just in surgery generally","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Verify that the surgeon is trained and experienced in performing the procedure you are considering.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C2","text":"Ask for certification information and the name of the body that certified the surgical setting","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Ask for certification information and the name of the certifying body when assessing a surgical setting.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C3","text":"Check that the surgeon who consults with you is the same person who will carry out the procedure","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Check that the surgeon you consult with, will be the same person carrying out the procedure.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C4","text":"Ask whether a doctor is always present in the clinic and whether a high dependency or intensive care unit exists","scope":"treatment_abroad","source":{"url":"https://www.bapras.org.uk/public/patient-information/cosmetic-surgery/cosmetic-surgery-abroad","host":"bapras.org.uk","quote":"Is there always a doctor in the clinic and is there a high dependency or intensive care unit?","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C5","text":"Ask whether the surgeon and the facility use a surgical safety checklist, which can reduce complications","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Do the surgeon and his/her facility use a safety checklist?","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"The offer claims to cure ankylosing spondylitis or reverse its damage","scope":"treatment_type","source":{"url":"https://www.nhs.uk/conditions/ankylosing-spondylitis/","host":"nhs.uk","quote":"There's no cure for AS and it's not possible to reverse the damage caused by the condition.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},{"id":"F2","text":"An advert or information that guarantees complete success should raise concerns","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Any advert or information that guarantees complete success should raise concerns.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"F3","text":"Forceful persuasion or cheap, time-limited offers pushing you into a quick decision","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Don’t be pressured into quick decisions either through forceful persuasion or cheap, time limited offers.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"warning_signs":{"status":"missing","reason":"no_official_source","checked_at":"2026-11-14","next_check_at":"2027-02-12"},"take_home":{"status":"ok","items":[{"id":"T1","text":"Home doctor needs the clinic's follow-up recommendations in a written discharge summary","document":"discharge summary","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"When you have treatment abroad, you must ask the treatment provider for their follow-up recommendations documented within a written discharge summary in English.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T2","text":"Ask for copies of all prescriptions before you leave","document":"prescription copies","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Remember to ask for copies of all your treatment records, including prescriptions, scans and x-rays before you leave.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T3","text":"Home doctor needs the dates for required blood tests and follow-up appointments","document":"written aftercare plan","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"This should include any medication and doses, as well as any dates that blood tests and follow-up appointments must be carried out.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1}},"parsed_details":{"procedure_type":"therapy","fields":{"anesthesia":["local"],"back_to_work_days":{"min":1,"max":3,"unit":"days","qualifier":"Depends on harvest site discomfort and infusion reaction; desk work resumes sooner than physical work."},"complication_rate_pct":{"min":10,"max":30,"unit":"percent","qualifier":"Mostly mild transient events (fever, headache, harvest site pain) within 30 days; serious events rare."},"contraindications":["Active infection","Current or past malignancy","Pregnancy or breastfeeding","Severe cardiac, renal or hepatic disease","Bleeding disorder or anticoagulant use","Uncontrolled immunosuppression or HIV","Allergy to anesthetic or product components"],"days_in_clinic":{"min":16,"max":33,"unit":"nights","qualifier":"16-33 nights: harvest, 2-4 week culture wait, infusion, post-infusion check."},"diagnostic_duration_minutes":null,"diagnostic_preparation":null,"diagnostic_referral_needed":null,"diagnostic_result_time_hours":null,"exercise_resume_weeks":{"min":1,"max":2,"unit":"weeks","qualifier":"Light activity first; harvest site healing and infusion tolerance determine return to full exercise."},"final_result_months":{"min":3,"max":6,"unit":"months","qualifier":"Any effect on symptoms is gradual and unproven; assessed by disease activity scores."},"fly_home_after_days":{"min":2,"max":5,"unit":"days","qualifier":"After post-infusion check and resolution of fever or harvest site pain."},"follow_up_visits":[{"purpose":"wound_check","after":{"min":2,"max":7,"unit":"days","qualifier":"Harvest site check in clinic before infusion."},"requirement":"routine"},{"purpose":"assessment","after":{"min":30,"max":90,"unit":"days","qualifier":"Disease activity review with CRP, ESR and symptom scores."},"requirement":"routine"},{"purpose":"result_review","after":{"min":90,"max":180,"unit":"days","qualifier":"Response evaluation with rheumatologist, may include repeat MRI."},"requirement":"routine"}],"indications":["Active ankylosing spondylitis refractory to NSAIDs"],"main_risks":["Infection, infusion reactions, bleeding or harvest-site pain.","Unknown long-term safety of stem cell products."],"pain":"Mild discomfort at the harvest site and cannula insertion; infusion itself is usually painless. Transient low-grade fever or headache can occur.","preparation":["Rheumatologist review of diagnosis and disease activity","Blood tests including CRP, ESR, infection screening","Recent pelvis and sacroiliac MRI","Review and adjust biologic and NSAID therapy","Stop blood thinners as advised","Fasting only if sedation is used"],"recovery_timeline":[{"phase":"Day 0 (harvest)","description":"Bone marrow or fat harvest under local anesthesia; cells sent for culture.","restrictions":["No driving after procedure","Rest for the day"]},{"phase":"Days 1-7 after harvest","description":"Mild harvest site soreness, possible transient fever or fatigue; return to light daily activity.","restrictions":["Avoid heavy lifting","Keep harvest site clean and dry"]},{"phase":"Weeks 1-4 culture wait","description":"Patient remains near clinic or returns home while cells are expanded.","restrictions":["Continue prescribed physiotherapy","Report fever or infection signs"]},{"phase":"Infusion day (about weeks 2-4)","description":"Intravenous cell infusion with observation for reactions.","restrictions":["No driving after infusion","Rest for the day"]},{"phase":"Weeks 1-12 after infusion","description":"Resume normal exercise and physiotherapy; gradual symptom assessment.","restrictions":["Report fever or infection signs"]},{"phase":"Months 3-6","description":"Evaluation of response and disease activity.","restrictions":[]}],"rehabilitation_days":{"min":3,"max":7,"unit":"days","qualifier":"Ordinary functional recovery after harvest and infusion; physiotherapy for spondylitis continues separately."},"result_longevity":"Not established; durability of any symptomatic benefit is unproven.","revision_rate_pct":null,"scars":"No visible scar; a small needle puncture mark at the harvest site fades within days.","sessions_or_stages":{"sessions":{"min":1,"max":2,"unit":"visits","qualifier":"Two visits for autologous cells; allogeneic product needs one."},"stages":[{"code":"harvest","label":"Cell harvest from bone marrow or fat","after":{"min":0,"max":0,"unit":"days","qualifier":"Day of treatment"}},{"code":"infusion","label":"Intravenous stem cell infusion","after":{"min":14,"max":28,"unit":"days","qualifier":"After 2-4 weeks of cell culture"}}],"qualifier":"Autologous cells are expanded in culture between harvest and infusion."},"success":{"metric":null,"value":null,"unit":null,"horizon":null,"population":"Adults with active AS refractory to or intolerant of NSAIDs","evidence_status":"not_proven"},"techniques":[{"name":"Intravenous mesenchymal stem cell infusion","suits_whom":"Active AS refractory to or intolerant of NSAIDs","recovery":"Brief observation; return to light activity within days."},{"name":"Intra-articular or sacroiliac joint cell injection","suits_whom":"Predominant sacroiliac joint inflammation","recovery":"Local soreness for a few days; light activity resumes quickly."}],"treatment_conditions":["day_case"],"treatment_duration_hours":{"min":2,"max":4,"unit":"hours","qualifier":"2-4 hours per visit; harvest or infusion, excluding weeks of cell culture."},"initial_assessment_documents":["Pelvis and sacroiliac joint MRI report","Pelvis X-ray report","HLA-B27 test result","Current biologic and NSAID treatment history","Rheumatologist's diagnosis report","Blood tests: CRP and ESR"],"travel_trips":{"min":1,"max":2,"one_trip_possible":true,"qualifier":"One 2-5 week trip covers both visits; two trips also possible."},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Confirm the surgeon is trained and experienced in the exact procedure you are considering, not just in surgery generally","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Verify that the surgeon is trained and experienced in performing the procedure you are considering.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C2","text":"Ask for certification information and the name of the body that certified the surgical setting","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Ask for certification information and the name of the certifying body when assessing a surgical setting.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C3","text":"Check that the surgeon who consults with you is the same person who will carry out the procedure","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Check that the surgeon you consult with, will be the same person carrying out the procedure.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C4","text":"Ask whether a doctor is always present in the clinic and whether a high dependency or intensive care unit exists","scope":"treatment_abroad","source":{"url":"https://www.bapras.org.uk/public/patient-information/cosmetic-surgery/cosmetic-surgery-abroad","host":"bapras.org.uk","quote":"Is there always a doctor in the clinic and is there a high dependency or intensive care unit?","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C5","text":"Ask whether the surgeon and the facility use a surgical safety checklist, which can reduce complications","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Do the surgeon and his/her facility use a safety checklist?","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"The offer claims to cure ankylosing spondylitis or reverse its damage","scope":"treatment_type","source":{"url":"https://www.nhs.uk/conditions/ankylosing-spondylitis/","host":"nhs.uk","quote":"There's no cure for AS and it's not possible to reverse the damage caused by the condition.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},{"id":"F2","text":"An advert or information that guarantees complete success should raise concerns","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Any advert or information that guarantees complete success should raise concerns.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"F3","text":"Forceful persuasion or cheap, time-limited offers pushing you into a quick decision","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Don’t be pressured into quick decisions either through forceful persuasion or cheap, time limited offers.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"warning_signs":{"status":"missing","reason":"no_official_source","checked_at":"2026-11-14","next_check_at":"2027-02-12"},"take_home":{"status":"ok","items":[{"id":"T1","text":"Home doctor needs the clinic's follow-up recommendations in a written discharge summary","document":"discharge summary","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"When you have treatment abroad, you must ask the treatment provider for their follow-up recommendations documented within a written discharge summary in English.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T2","text":"Ask for copies of all prescriptions before you leave","document":"prescription copies","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Remember to ask for copies of all your treatment records, including prescriptions, scans and x-rays before you leave.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T3","text":"Home doctor needs the dates for required blood tests and follow-up appointments","document":"written aftercare plan","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"This should include any medication and doses, as well as any dates that blood tests and follow-up appointments must be carried out.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"alternatives":{"status":"ok","items":[{"id":"A1","text":"Your symptoms need more than first-line anti-inflammatory drugs","name":"Biologic medicines","source":{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10874590/","host":"pmc.ncbi.nlm.nih.gov","quote":"First-line treatments such as non-steroidal anti-inflammatory drugs are no longer the only options, even though disease-modifying anti-rheumatic drugs and biologics, especially tumor necrosis factor blockers, have been developed.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200},"operation_id":null},{"id":"A2","text":"You want exercise, stretching, and posture maintenance for symptom management","name":"Physical therapy","source":{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10874590/","host":"pmc.ncbi.nlm.nih.gov","quote":"Physical therapy, which emphasizes consistent exercise, stretches, and posture maintenance, is extremely helpful in managing AS.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200},"operation_id":null},{"id":"A3","text":"Your symptoms require medication to treat pain and inflammation","name":"NSAIDs","source":{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10874590/","host":"pmc.ncbi.nlm.nih.gov","quote":"NSAIDs, DMARDs, such as methotrexate, sulfasalazine, hydroxychloroquine, leflunomide, azathioprine, cyclosporine, tacrolimus biologics such as TNF blockers, and IL17-A antagonists are used as medications to treat pain and inflammation.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200},"operation_id":null}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"technique_details":{"status":"ok","items":[{"id":"intravenous-mesenchymal-stem","name":"Intravenous mesenchymal stem cell infusion","how_it_works":{"status":"missing","reason":"no_official_source"},"recovery_daily":{"status":"missing","reason":"no_official_source"}},{"id":"intra-articular","name":"Intra-articular or sacroiliac joint cell injection","how_it_works":{"status":"missing","reason":"no_official_source"},"recovery_daily":{"status":"missing","reason":"no_official_source"}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1}}},"techniques":[{"id":"intravenous-mesenchymal-stem","name":"Intravenous mesenchymal stem cell infusion","how_it_works":{"status":"missing","reason":"no_official_source"},"recovery_daily":{"status":"missing","reason":"no_official_source"},"suits_whom":"Active AS refractory to or intolerant of NSAIDs","price_from":{"status":"missing","reason":"not_collected"},"recovery":"Brief observation; return to light activity within days."},{"id":"intra-articular","name":"Intra-articular or sacroiliac joint cell injection","how_it_works":{"status":"missing","reason":"no_official_source"},"recovery_daily":{"status":"missing","reason":"no_official_source"},"suits_whom":"Predominant sacroiliac joint inflammation","price_from":{"status":"missing","reason":"not_collected"},"recovery":"Local soreness for a few days; light activity resumes quickly."}],"alternatives":{"status":"ok","items":[{"id":"A1","text":"Your symptoms need more than first-line anti-inflammatory drugs","name":"Biologic medicines","source":{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10874590/","host":"pmc.ncbi.nlm.nih.gov","quote":"First-line treatments such as non-steroidal anti-inflammatory drugs are no longer the only options, even though disease-modifying anti-rheumatic drugs and biologics, especially tumor necrosis factor blockers, have been developed.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200},"operation_id":null},{"id":"A2","text":"You want exercise, stretching, and posture maintenance for symptom management","name":"Physical therapy","source":{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10874590/","host":"pmc.ncbi.nlm.nih.gov","quote":"Physical therapy, which emphasizes consistent exercise, stretches, and posture maintenance, is extremely helpful in managing AS.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200},"operation_id":null},{"id":"A3","text":"Your symptoms require medication to treat pain and inflammation","name":"NSAIDs","source":{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10874590/","host":"pmc.ncbi.nlm.nih.gov","quote":"NSAIDs, DMARDs, such as methotrexate, sulfasalazine, hydroxychloroquine, leflunomide, azathioprine, cyclosporine, tacrolimus biologics such as TNF blockers, and IL17-A antagonists are used as medications to treat pain and inflammation.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200},"operation_id":null}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"diagnostic":{"status":"not_applicable"},"country":{"why":{"status":"missing","reason":"no_official_source","checked_at":"2026-11-12","next_check_at":"2027-02-10"},"travel":{"status":"ok","items":[{"id":"V1","item":"visa","audience":"uk","volatile":true,"text":"British travelers visiting Mexico as tourists do not need a visa","source":{"url":"https://www.gov.uk/foreign-travel-advice/mexico/entry-requirements","host":"gov.uk","quote":"If you’re visiting Mexico as a tourist, you do not need a visa.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}},{"id":"V2","item":"passport_validity","audience":"uk","volatile":true,"text":"Your passport must be valid for the whole length of your stay in Mexico","source":{"url":"https://www.gov.uk/foreign-travel-advice/mexico/entry-requirements","host":"gov.uk","quote":"To enter Mexico, your passport must be valid for the duration of your stay.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}},{"id":"V3","item":"passport_validity","audience":"us","volatile":true,"text":"For air travel, a passport book is required to enter Mexico","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Mexico.html","host":"travel.state.gov","quote":"Air travel: You need a passport book to enter Mexico.","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V4","item":"arrival_form","audience":"uk","volatile":true,"text":"British nationals entering Mexico by land must complete an immigration form online","source":{"url":"https://www.gov.uk/foreign-travel-advice/mexico/entry-requirements","host":"gov.uk","quote":"British nationals entering Mexico by land must fill in an immigration form online.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}},{"id":"V5","item":"medicines","audience":"us","volatile":false,"text":"U.S. travelers can be arrested for bringing over-the-counter or prescription medicine that is illegal in Mexico, even with a U.S. doctor's letter or prescription","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Mexico.html","host":"travel.state.gov","quote":"You could be arrested if your over the counter or prescription medicine is illegal in Mexico, even with a U.S. doctor’s letter or prescription.","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V6","item":"land_border","audience":"us","volatile":false,"text":"All travelers entering Mexico by land need a passport book or card and must apply for an FMM entry permit online or from an INM office","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Mexico.html","host":"travel.state.gov","quote":"By land: All travelers are required to have a passport book or card and apply for an FMM, online or from an INM office, including travelers who are only staying within 12 miles from the border (or 20 kilometers)","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V7","item":"emergency_number","audience":"all","volatile":false,"text":"Dial 911 in Mexico and ask for an ambulance","source":{"url":"https://www.gov.uk/foreign-travel-advice/mexico/health","host":"gov.uk","quote":"Dial 911 and ask for an ambulance.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2026-12-12","version":1},"other_countries_with_page":["colombia","india","poland","thailand","turkey","ukraine"]},"often_combined_with":{"status":"missing","reason":"not_collected"},"reviews":{"avg_rating":5,"count":4,"scope":"clinic","rating_scale":5,"pros":{"status":"missing","reason":"not_collected"},"cons":{"status":"missing","reason":"not_collected"}},"current":{"seo_text":"

Stem cell therapy for ankylosing spondylitis in Mexico typically costs from _op_1484_price_from_ to _op_1484_price_to_. The final price depends on the cell count, delivery method, and clinic location in hubs like Monterrey or Playa del Carmen. In the US, similar procedures cost around _price_compare_US_average_ on average. Patients save around _price_percent_discount_% compared to the US. Most packages include physician consultations and airport-to-clinic transfers.

\n\n\n\n

Bookimed Expert Insight: Choosing a clinic with CSG accreditation ensures high safety standards without the premium US price. Facilities like Advanced Regenerative Center offer specialized orthopedic protocols for approximately $6,000. While some clinics like Immunotherapy Regenerative Medicine include personalized metabolic protocols, others focus strictly on cell delivery. Patients should confirm if their quote includes follow-up care to ensure the best long-term value for systemic treatments.

","faq":[{"q":"What Should You Know about Mexico before the Trip?","a":"

Currency

Mexican peso (you also can pay for services in dollars)

Best period for the trip

December-April

Language

Spanish (most of medical staff speaks English fluently)

Visa

required for some countries

Time difference with Europe

7 hours

Time difference with the USA

1 hour

Capital

Mexico City

Medical tourism center

Mexico City

Popular resorts

Central and Southern Mexico

"},{"q":"What hotel services are provided here?","a":"

In Mexico, hotels of different price ranges and service levels are presented. Most tourists choose 4 and 5 star hotels with all-inclusive meals. Such hotels have everything for a comfortable stay: varied food, a large well-groomed territory, animation for children and adults. Some hotels have their own water park, which guests can use for free. Budget travelers can afford to book an economical 3-star hotel with half board or no meals at all.

"},{"q":"What Documents Are Required to Apply for a Visa to Mexico for Treatment?","a":"

Visas for travel to Mexico require a number of documents. Lists of documents includes:

"}],"h2":[{"text":"Como funciona","kind":"content"},{"text":"Qual é o Custo de Terapia com células estaminais para espondilite anquilosante em México? Descubra Agora","kind":"content"},{"text":"Descubra as Melhores Clínicas de Terapia com células estaminais para espondilite anquilosante em México: 5 opções Verificadas e Preços","kind":"content"},{"text":"Visão geral de Terapia com células estaminais para espondilite anquilosante em México","kind":"content"},{"text":"Obtenha uma avaliação médica para Terapia com células estaminais para espondilite anquilosante em México: escolha seu especialista entre os melhores da área","kind":"content"},{"text":"Histórias em vídeo de pacientes da Bookimed","kind":"content"},{"text":"Avaliações sobre Bookimed: descubra percepções de pacientes","kind":"content"},{"text":"Compartilhar este conteúdo","kind":"content"},{"text":"FAQ sobre Terapia com células estaminais para espondilite anquilosante em México","kind":"content"},{"text":"Obtenha uma consulta gratuita","kind":"content"}]},"placeholders":{"price_from":"{{price_from}}","clinics_count":"{{clinics_count}}","cities_count":"{{cities_count}}","savings_pct":"{{savings_pct}}","data_date":"{{data_date}}"},"legal":{"restricted_markets":{"status":"missing","reason":"not_collected"}},"conflicts":[]}