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Doctor Brenda Pastrana is a mexican surgical Oncologist. 

Medical background.

Centro Medico Nacional 20 de Noviembre Issste, Surgical Oncologist in 2020.

Title by Universidad Autónoma de México UNAM.

Surgical Residency Instituto Mexicano del Seguro Social. 2015.

Title by Universidad de Quintana Roo. 

Board Certified by Conacem from 2020 to 2025 number 2171 

Board Certified by Conacem from 2025 to 2030 number 2171

Member of SMEO. Sociedad Mexicana de Oncología. 

University teacher at Universidad Anahuac of Medicine since 2020.

O Professor Ralf Buhl é um neurocirurgião de renome mundial com mais de 20 anos de experiência. O Dr. Buhl lidera o Departamento de Neurocirurgia no Solingen Klinikum. A sua reputação alcança a China e os EUA, onde ministra palestras sobre neurocirurgia.

Especialidade

O Dr. Buhl é especialista em métodos não invasivos para o tratamento de hérnia discal, tumores cerebrais e medulares. O médico oferece tratamento para distúrbios do sistema nervoso periférico e realiza microcirurgias com navegação assistida por computador.

O Dr. Ralf Buhl realizou mais de 4.000 neurocirurgias bem-sucedidas. Entre os seus pacientes estão políticos famosos, empresários, músicos e atores. Em 2015, uma estrela de Hollywood, George Clooney, teve dores intensas nas costas e foi tratado pelo Professor Buhl.

Atividade científica

O Dr. Buhl realiza trabalhos científicos e pesquisas no tratamento de cavernomas intracranianos, tratamento cirúrgico de metástases cerebrais e outras áreas da neurocirurgia.

O Professor Buhl foi cofundador do Fundo dedicado ao estudo de tumores cerebrais.

Medical Specialization Thesis Title and Advisor :  Histopathologic Comparison of Intracerebral Microballoon Dissection Method and Classical Corticotomy in Rat Brain . Ondokuz Mayıs Üniversitesi Tıp Fakültesi Beyin ve Sinir Cerrahisi AD 2006, 

Thesis Advisor:  Assoc. Prof. Dr. Alparslan Senel PhD Thesis Title and Advisor: Deep brain stimulation of the subthalamic nucleus: clinical and scientific aspects. Maastricht University Department of Neuroscience 2016, Thesis Supervisor: Prof. Dr. Yasin Temel  

Asst. Assoc. Dr. OMU Faculty of Medicine, Department of Neurosurgery Guest Lecturer Maastricht University Neuroscience and Neurosurgery Clinics, NETHERLANDS 2009 2011 

Assoc. Dr. OMU Faculty of Medicine, Department of Neurosurgery 2015 

Prof. Dr. OMU Faculty of Medicine, Department of Neurosurgery 2022

Guest Lecturer Atlas University Faculty of Medicine, Istanbul 2021-2024 

Rector of Atlas University 2024 -

Directed specialty theses: 

1.Comparative results of plastic cap and bone cement used for permanent electrode fixation in deep brain stimulation surgeries. Ondokuz Mayıs University Faculty of Medicine, Department of Neurosurgery 2019, Thesis Student: Dr. Önder Taşkın 

2.The effect of deep brain stimulation surgery on the volumes of brain nuclei in Parkinson's patients. Ondokuz Mayıs University Faculty of Medicine, Department of Neurosurgery 2024, Thesis Student: Dr. Muhammet Dirlik 

Administrative Duties :  

Rector of Atlas University (2024, currently)

-Founding Member - Founding Board Member of the International Deep Brain Stimulation Association (20202023), (2023, currently) 

-Functional group committee member of the European Association of Neurosurgery (EANS) (2020, currently) 

-President-Founding Member of the National Deep Brain Stimulation Association (2105-2018), (2018-2021), (2021, Ondokuz Mayıs University Neuromodulation Center Responsible (2018, currently) 

-Turkish Academy of Neurosurgery Board Member (2022, currently)

 -Turkish Neurosurgical Association Stereotactic, Functional, Pain and Epilepsy Surgery Teaching and Education Group Chairman (2019, 2022), 2nd. Chairman (2017-2019), Secretary (2013- 2015 / 2015 - 2017) 

- Board Member of Neuromodulation Research and Education Association (Secretary, 2020, 2022), (Secretary, 2018-2020) 

-Ondokuz Mayıs University Continuing Education Center Board Membership (2012-2015/ 2015-2018) 

-Ondokuz Mayıs University Black Sea Advanced Technology Application and Research Center (KİTAM) Board Membership (2016-2017)

 -Turkish Neurosurgical Association Professional Personnel Rights Board Membership (2013-Present) 

Other duties: -Deep brain stimulation training, consultancy and supervision (2014-present) 

Universities, hospitals and institutions consulted 

1. Hacettepe University Faculty of Medicine 

2. Akdeniz University Faculty of Medicine 

3. Uludağ University Faculty of Medicine 

4. Atlas University Faculty of Medicine Medicine Medicine Hospital 

5. Baku National Oncology Hospital, Azerbaijan

 6. Erciyes University Faculty of Medicine

 7. Fırat University Faculty of Medicine

 8. Health Sciences University Tepecik Training and Research Hospital, Izmir

 9. Health Sciences University City Hospital, Ankara 

10. Adana Başkent University Hospital 

11. Medtronic Inc 

12. Boston Scientific 

13. Dokuz Eylül University Faculty of Medicine 

Bilimsel Kuruluşlara Üyelikler :  

1. Türk Nöroşirürji Derneği 

2. Türk Nöroşirürji Derneği Stereotaktik, Fonksiyonel, Ağrı ve Epilepsi Cerrahisi     Öğretim ve Eğitim Grubu 

3. Uluslararası Derin Beyin Stimülasyonu Derneği 

4. National Deep Brain Stimulation Society 

5. Turkish Neurosurgical Society Neurooncological Surgery Teaching and Training Group 

6. European Society for Stereotactic and Functional Neurosurgery (ESSFN) 

7. International Parkinson and Movement Disorder Society (MDS)

8. Mediterranean Neuroscience Society (MNS) 

9. World Society for Stereotactic and Functional Neurosurgery (WSSFN) 

10. International Neuromodulation Society (INS)

11. Neuromodulation Research and Education Association 

Undergraduate and graduate level courses given in the last 2 years 

- Neuromodulation (D-5) 

- Stereotactic surgical methods in neurological diseases (D-5) 

- Surgical treatment of movement disorders - Bedside practice (D-5) 

- Head traumas (D-5) 

- Head traumas (D-3) 

- Medicine and Poetry (D-1) * For D-5, 9 internship groups are taught in one academic year. 

Summary of academic activity (January 2024) 

A. International articles: 46 

B. International proceedings: 44 

C1. National book editorship: 2 

C2. International book chapter: 2 

C3. National book chapter: 13 

D. National articles: 12 

E. National proceedings: 45 

F. Organized meetings: 18 (7 international, 11 national) 

G. Invited talks: 71 (13 international, 58 national) 

h index: 12 (Web of science), 12 (Scopus), 16 (Scholar) 

Number of citations: 332 (Web of science), 342 (Scopus), 595 (Scholar) 

A. Articles published in international refereed journals : 

1. Eser P, Kocabicak E, Bekar A, Temel Y. Insights into neuroinflammatory mechanisms of deep brain stimulation in Parkinson's disease. Exp Neurol. 2024 Jan 8:114684. 

2. Eser P, Kocabicak E, Bekar A, Temel Y. Interplay between neuroinflammatory pathways and Parkinson's disease.Exp Neurol. 2024 Feb;372:114644.  

3. Yasar OC, Ozturk S, Kemal O, Kocabicak E. Effects of Subthalamic Nucleus Deep Brain Stimulation Surgery on the Formant Frequencies of Turkish Vowels and Vowels. Turk Neurosurg. 2022;32(5):764-772. 

4. Taşkın O, Kocabıcak E, Öztürk S, Yıldız O, Temel Y. Electrode Fixation with Bone Cement or Stimloc® in Deep Brain Stimulation Surgery: A Comparative Study. Turk Neurosurg. 2022;32(3):449-458. 

5. Nassehi B, Assadnejad T, Yildiz O, Aygun D, Kocabicak E. Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease with Severe Axial Symptoms and Suboptimal Levodopa Response. Turk Neurosurg. 2022;32(3)

6. Nassehi B, Kocabicak E, Temel Y, Hescham S. Alteration of Neurogenesis and Pathologic Markers in Alzheimer's Disease After Deep Brain Stimulation. Turk Neurosurg. 2022;32(4)

7. Habets JGV, Herff C, Fasano AA, Beudel M, Kocabicak E, Schnitzler A, Snineh MA, Kalia SK, Ramirez-Gómez C, Hodaie M, Munhoz RP, Rouleau E, Yildiz O, Linetsky E, Schuurman R, Hartmann CJ, Lozano AM, De Bie RMA, Temel Y, Janssen MLF. Multicenter Validation of Individual Preoperative Motor Outcome Prediction for Deep Brain Stimulation in Parkinson's Disease. Stereotact Funct Neurosurg. November 2021, 25: 1-9. 

8. Öztürk S, Temel Y, Aygün D, Kocabıçak E. Deep Brain Stimulation of Globus Pallidus Internus for Secondary Dystonia: Clinical Cases and Systematic Review of the Literature on the Efficacy of Globus Pallidus Internus and Subthalamic Nucleus. World Neurosurg. 2021 Oct

9. Kocabicak E, Yildiz O, Aygun D, Temel Y. Effects of Deep Brain Stimulation of the Subthalamic Nucleus on Postoperative Levodopa Response: One Year Follow-up. Turk Neurosurg. 2021;31(1)

10. Kaya MO, Ozturk S, Ercan I, Gonen M, Erol FS, Kocabicak E. Statistical Shape Analysis of the Subthalamic Nucleus in Patients with Parkinson's Disease. World Neurosurgery. World Neurosurg. 2019 

11. Kocabicak E, Alptekin O, Aygun D, Yildiz O, Temel Y. Microelectrode recording for deep brain stimulation of the subthalamic nucleus in patients with advanced Parkinson's disease: advantage or waste of time? Turk Neurosurg. 2019;29

12. Aygun D, Dere U A, Yildiz O, Temel Y, Kocabicak E. Characterizing the effect of intraoperative microelectrode recording-induced microlesion on motor symptoms in patients with Parkinson's disease undergoing deep brain stimulation of the subthalamic nucleus. Turk Neurosurg. 2019;29

13. Wetzelaer P, Bouwens VAN DER Vlis T, Tönge M, Ackermans L, Kubben P, Evers S, Kocabicak E, Temel Y. Management of equipment-related infections after DBS surgery: A cost analysis. Turk Neurosurg. 2018;28

14. Alptekin O, Kocabicak E, Gubler FS, Ackermans L, Kubben PL, Temel Y. Perioperative Technical Complications in Deep Brain Stimulation Operations. Turk Neurosurg. 2018;28

15. Aygun D, Kocabicak E, Yildiz MO, Temel Y. The Effect of Age and Disease Duration on Levodopa Response in Patients with Advanced Parkinson's Disease for Deep Brain Stimulation of the Subthalamic Nucleus. 

16. Akpinar C K, Aygun D, Kocabicak E, Onar M K. Dopamine dysregulation syndrome after subthalamic nucleus deep brain stimulation: A case report. Noro Psychiatr Ars. 2015 Dec

17. Tonge M, Kocabicak E, Ackermans L, Kuijf, M, Temel Y. Final electrode position in subthalamic nucleus deep brain stimulation surgery: comparison of indirect and direct targeting methods. Turk Neurosurg. 

18. Tonge M, Ackermans L, Kocabicak E, van Kranen-Mastenbroek V, Kuijf M, Oosterloo M, Kubben P, Temel Y. A detailed analysis of intracerebral hemorrhages in DBS operations. Clin Neurol Neurosurg. 2015 Dec

19. Kocabicak E, Alptekin O, Ackermans L, Kubben P, Kuijf M, Kurt E, Esselink R, Temel Y. Is there still a need for microelectrode recording because the subthalamic nucleus is well visualized by high field MR imaging? Front Integr Neurosci.(Accepted July 15, 2015) 

20. Yarar E, Kuruoglu E, Kocabıcak E, Altun A, Genc E, Ozyurek H, Kefeli M, Marangoz AH, Aydin K, Cokluk C. Electrophysiological and histopathological effects of mesenchymal stem cells in the treatment of experimental rat sciatic nerve injury model. Int J Clin Exp Med. 2015 Jun 15

21. Kocabicak E, Jahanshahi A, Schonfeld L, Hescham SA, Temel Y, Tan S. Deep brain stimulation of the rat subthalamic nucleus caused inhibition of median raphe serotonergic and dopaminergic neurotransmission. Turk Neurosurg 2015

22. Kocabicak E, Temel Y, Höllig A, Falkenburger B, Tan SKh. Current perspectives on deep brain stimulation for severe neurological and psychiatric disorders. Neur. Pschy. Disease and treatment 2015 

23. Lim LW, Janssen ML, Kocabicak E, Temel Y. Antidepressant activity by stimulation of the ventromedial prefrontal cortex and nucleus accumbens is associated with neural activation in the subthalamic nucleus of rats. Behav Brain Res. 2015 

24. Kocabicak E, Terzi M, Akpinar K, Paksoy K, Cebeci I, Iyigun O. Restless Leg Syndrome and Its Quality in Lumbar Radiculopathy Patients. Behavioural Neurology 2014

25. Kocabicak E, Aygun D, Ozaydin I, Jahanshahi A, Onar M, Tan S K, Boke O, Kurt M, Guz H, Terzi M, Alptekin O, Temel Y Is the probe eye subthalamic nucleus length on T2W MRI consistent with microelectrode recording in patients undergoing deep brain stimulation for advanced Parkinson's disease? Turk Neurosurg. 2013;23(5)

26. Duran L, Balci K, Kati C, Akdemir H U, Kocabicak E, Dogruel C. Does admission blood pressure have prognostic value in patients with subarachnoid hemorrhage: an emergency department experience. J Clin Hypertens (Greenwich). 2013 Oct;15(10)

27. Kocabicak E, Temel Y. Deep brain stimulation of the subthalamic nucleus in Parkinson's disease; Surgical technique, tips, tricks and complications. Clin Neurol Neurosurg. 2013 Nov;115(11)

28. Camlidag I, Kocabicak E, Sahin B, Jahanshahi A, Incesu L, Aygun D, Yildiz O, Temel Y, Belet U. Volumetric analysis of subthalamic and red nuclei based on magnetic resonance imaging in patients with Parkinson's disease. Int J Neurosci. 2014 Apr;124(4)

29. Jahanshahi A, Schonfeld L, Janssen ML, Hescham S, Kocabicak E, Steinbusch HW, van Overbeeke JJ, Temel Y. Electrical stimulation of the motor cortex increases progenitor cell migration in adult rat brain. Exp Brain Res. 2013 Nov;231(2)

30. Kocabicak E, Aygun D, Alptekin O, Guz H, Kurt M, Sarihasan B, Temel Y Conversion of local anesthetic-guided deep brain stimulation of the subthalamic nucleus to general anesthesia. J Neurol Surg A Cent Eur Neurosurg 2013, Sep;74(5):332-4.  

31. Jahanshahi A, Vlamings R, van Roon-Mom WM, Faull RL, Waldvogel HJ, Janssen ML, Yakkioui Y, Zeef DH, Kocabicak E, Steinbusch HW, Temel Y. Changes in brainstem serotonergic and dopaminergic cell populations in experimental and clinical Huntington's disease. 

32. Aydin K, Kocabicak E, Altun A, Ozaydin I, Yarar E, Cokluk C. Use of Topical Landmarks in Percutaneous Projection of Intracranial Tumors in Neurosurgical Oncology. Turk Neurosurg. 2012;22(3)

33. Aydın K, Çokluk C, Pişkin A, Kocabıcak E. Ultrasonographic control of transverse carpal ligament incision with limited single skin incision during carpal tunnel surgery. Turk Neurosurg. 2007 Jul;17(3)

34. Alptekin O, Gubler F, Ackermans L, Kubben P, Kuijf M, Kocabicak E, Temel Y. Stereotactic Accuracy and Frame Mounting: a phantom study. Surg Neurol Int. 2019 Apr 24;10:67. 

35. Gubler FS, Ackermans L, Kubben PL, Damci A, Kuijf ML, Oosterloo M, Vermeulen RJ, Hescham S, Kocabicak E, Kurt E, Temel Y. Infections in deep brain stimulation: Shaving versus not shaving. Surg Neurol Int. 2017 Oct 10;8:249. 

36. Dere U Akin, Tonge M, Temel Y, Kocabicak E. Unusual length of the AC-PC line and the importance of direct targeting. OAJJN. 2016;1(4)

37. Aygun D, Kocabicak E, Yildiz O, Onar MK, Guz H, Boke O, Kurt M, Temel Y. Syncope associated with subthalamic nucleus deep brain stimulation in a patient with Parkinson's disease. Case Rep Neurol Med. 2013 

38. Kocabicak E, Terzi M, Alptekin O, Temel Y. Targeting thalamic tremor cells in deep brain stimulation for multiple sclerosis-induced complex tremor. Surg Neurol Int. 2013. 

39. Kocabicak E, Tan SK, Temel Y. Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: Why is it so successful? Surg Neurol Int. 2012;3(Suppl 4)

40. Kocabicak E. Tan SK, Temel Y. Aydın K, Kocabicak E, Çokluk C, Kuruoğlu E, Yıldız L, Marangoz A.H. Cerebral Intraparenchymal Epidermoid Tumor: A Case Report.Chirurgia 2012 October

41. Aydın K, Çokluk C, Kocabıcak E, Çelik B, Taşlak Şengül A. Cervical Screw Extrusion into the Trachea and Perforation: A Case Report. Chirurgia 2012 Oct

42. Cervical Ependymoma: A Case Report and Review of the Literature. Kocabicak E, Cengiz Çokluk,Kerameddin Aydın,Yaşar Bayri,Yurdanur Süllü Journal of Experimental and Clinical Medicine 2010.27; 

43. Nonanastomotic Indirect Bypass Surgery in Surgical Treatment of Malignant Glial Tumors. Cengiz Çokluk,Kerameddin Aydın, Kocabicak E. Journal of Experimental and Clinical Medicine 2010. 

44. On-Off Malignancy in a Pediatric Shunt. Cengiz Çokluk,Kerameddin Aydın, Kocabicak E. Journal of Experimental and Clinical Medicine 2009. 

45. Vibration Producing Dissector in Dissection and Separation of High Grade Glial Tumors from Brain Tissue. Cengiz Çokluk,Kerameddin Aydın, Kocabicak E. Journal of Experimental and Clinical Medicine 2009. 

46. Geriatric Traumatic Acute Subdural Haematomas: A Retrospective Study. Kocabicak E, Ercan Yarar,Cengiz Çokluk,Kerameddin Aydın. Journal of Experimental and Clinical Medicine 2009. 

B. Abstracts presented at international meetings 

1. Kaya Mehmet Onur, Ozturk Sait, Erol Fatih Serhat, Gönen Murat, Ercan Ilker, Kocabicak Ersoy. Statistical Shape Analysis of Subthalamic Nucleus in Patients with Parkinson’s Disease. OP 01, 4th clinical neuroscience course. ‘Current state and future in deep brain stimulation in Parkinson’s disease’, 17-19 October 2019. Anemon Hotel, Samsun, Turkey 

2. Ozgenc Aysun, Taskin Onder, Yildiz Mustafa Onur, Aygün Dursun, Kocabicak Ersoy. Parkinson’s Disease and Neuromodulation Nursing. OP 02, 4th clinical neuroscience course. ‘Current state and future in deep brain stimulation in Parkinson’s disease’, 17-19 October 2019. Anemon Hotel, Samsun, Turkey 

3. Yasar Ozlem, Kemal Ozgur, Kocabicak Ersoy. Effects of Deep Brain Stimulation of the Subthalamic Nucleus on Acoustic Characteristics of Voice Production:Preliminary Results. OP 03, 4th clinical neuroscience course. ‘Current state and future in deep brain stimulation in Parkinson’s disease’17-19 October 2019. Anemon Hotel, Samsun, Turkey 

4. Nassehi Behrad, Kocabicak Ersoy. The Alteration of Neurogenesis and Pathological Markers in Alzheimer's Disease after Deep Brain Stimulation. OP 04, 4th clinical neuroscience course. ‘Current state and future in deep brain stimulation in Parkinson’s disease’17-19 October 2019. Anemon Hotel, Samsun, Turkey 

5. Sücüllü Karadag Yesim, Divanlioglu Denizhan, Öztekin Zeynep Nese, Belen Ahmet Deniz, Kocabicak Ersoy. Medical and Device-Guided Therapies and Deep BrainStimulation in Parkinson's Disease: Experience of a Tertiary Center from Turkey. OP 05, 4th clinical neuroscience course. ‘Current state and future in deep brain stimulation in Parkinson’s disease’17-19 October 2019. Anemon Hotel, Samsun, Turkey 

6. Pilan Kubra, taskin Onder, Yildiz Mustafa Onur, Ozgenc Aysun, Kocabicak Ersoy. Effect of Subthalamic Nucleus Deep Brain Stimulation on Nutritional Status and Habits in Parkinson's Patients. OP 06, 4th clinical neuroscience course. ‘Current state and future in deep brain stimulation in Parkinson’s disease’17-19 October 2019. Anemon Hotel, Samsun, Turkey 

7. Assadnejad Taha, Nassehi Behrad, Aygun Dursun, Yildiz Mustafa Onur, Kocabicak Ersoy. Unilateral Globus Pallidus Interna Deep BrainStimulation in Post Stroke Dystonic Tremor: Case Report. OP 09, 4th clinical neuroscience course. ‘Current state and future in deep brain stimulation in Parkinson’s disease’17-19 October 2019. Anemon Hotel, Samsun, Turkey 

8. Ozturk Sait, Gönen Murat, Erol Fatih Serhat, Kocabicak Ersoy. When Internal Pulse Generator Should Be Activated Following Deep Brain Stimulation in Parkinson's Disease? OP 10, 4th clinical neuroscience course. ‘Current state and future in deep brain stimulation in Parkinson’s disease’17-19 October 2019. Anemon Hotel, Samsun, Turkey

9. Yildiz Mustafa Onur, Taskin Onder, Aygun Dursun, Kocabicak Ersoy. Long-Term Outcomes of Deep Brain Stimulation in Parkinson's Disease: Single Center Experience. OP 13, 4th clinical neuroscience course. ‘Current state and future in deep brain stimulation in Parkinson’s disease’17-19 October 2019. Anemon Hotel, Samsun, Turkey 

10. Ulutabanca Halil, Gultekin Murat, Kocabicak Ersoy. Follow-Up Effect of Deep Brain Stimulation of the Thalamic Ventralis Intermedius Nucleus in a Patient with Bipolar Disorder and Essential Tremor. OP 15, 4th clinical neuroscience course. ‘Current state and future in deep brain stimulation in Parkinson’s disease’17-19 October 2019. Anemon Hotel, Samsun, Turkey 

11. Assadnejad Taha, Nassehi Behrad, Yildiz Mustafa Onur, Aygun Dursun, Kocabicak Ersoy. Subthalamic Nucleus Deep Brain Stimulation in aPatient with Severe Axial Symptoms and Minimal Levodopa Responsive Parkinson's Disease. OP 16, 4th clinical neuroscience course. 'Current state and future in deep brain stimulation in Parkinson's disease'17-19 October 2019. Anemon Hotel, Samsun, Turkey 

12. Ozturk S, Aygun D, ​​Temel Y, Kocabicak E. Deep brain stimulation of the globus pallidus interna with microelectrode recording for secondary dystonia: clinical reports and review of the literature. XXXIIIrd of the ESSFN, Edinburgh, Scotland 2018

13. Alptekin O, Gubler F, Kocabicak E, Ackermans L, Kubben P, Temel Y. Impact of Radiological Image Slice Thickness on Stereotactic Accuracy: a phantom study. XXXIIIrd of the ESSFN, Edinburgh, Scotland 2018 

14. Gultekin M, Ulutabanca H,Selcuklu A, Mirza M, Temel Y, Kocabicak E. Deep brain stimulation of the globus pallidus interna with microelectrode recording for MyoclonusDystonia (DYT- 11): One year Outcome in Two Patients. 70th AAN Annual meeting, Los Angeles USA 2018, P5-055 

15. Kocabicak E, Yildiz M O, Aygun D, ​​Temel Y. The clinical effects of preoperative levodopa response for deep brain stimulation of the subthalamic nucleus for patients with Parkinson's disease in the postoperative period 3rd clinical neuroscience course, Turkey 2017, OP-14 

16. Sen S, Terzi M, Yildiz M O, Temel Y, Kocabicak E. Deep brain stimulation for Multiple Sclerosis related tremor: clinical reports. 3rd clinical neuroscience course, Turkey 2017, OP-16 

17. Gönen M, Ozturk S, Balgetir F, Aytac E, Kocabicak E. Pseudobulbar Laughter Induced by Stimulation of Subthalamic Nucleus: Case Report. 3rd clinical neuroscience course, Turkey 2017, OP-03 

18. Ozturk S, Gonen M, Korkmaz S, Erol F S, Kocabicak E. Early-term results of deep brain stimulation in patients with Parkinson's Disease: Elazığ Experience. 3rd clinical neuroscience course, Turkey 2017, OP-05

19. Turgut E, Ozkaynak S, Kocabicak E, Baysal O G, Temel Y, Ucar T. The Early Results of STN DBS in Parkinson's Disease: Akdeniz University Experience. 3rd clinical neuroscience course, Turkey 2017, OP-08 

20. Turgut E, Parlak H, Agar A, Sarikcioglu L, Ucar T, Kocabicak E, Temel Y. The Effects of Deep Brain Stimulation of the Substantia Nigra Pars Reticulata in 6-OHDA Parkinsonism Model in Rats. 3rd clinical neuroscience course 3rd clinical neuroscience course, Turkey 2017, OP13 

21. Dere U A, Tonge M, Temel Y, Kocabicak E.Unusual Length of the Ac-Pc Line and the Importance of Direct Targeting. 3rd clinical neuroscience course 3rd clinical neuroscience course, Turkey 2017, PP-06 

22. Taskin O, Aygun D,Temel Y, Kocabicak E. Comparative results of plastic cap and bone cement usage in permanent electrode fixation of deep brain stimulation. WFNS XVI. World Congress of Neurosurgery Istanbul-Turkey, 20-25 August, 2017-OP 

23. Ulutabanca H, Gultekin M, Kucuk A, Ciftci M, Selcuklu A, Temel Y, Kocabicak E Confirmation of Electrode Localization by Fusion Between Preoperative T2W MRI and Postoperative CT Scan on Parkinson Cases Who Underwent STN DBS. WFNS XVI. World Congress of neurosurgery Istanbul-turkey, 20-25 August, 2017 –OP 

24. Tonge M, Lindhout J, Kocabicak E, Dere U A, Temel Y. Effect of frontal angle of approach on microelectrode recording and clinical parameters in STN-DBS surgery . XVII. WSSFN Congress, Berlin, Germany 2017, #10653 PP-031 

25. Kocabicak E, Aygun D, ​​Yildiz O, Temel Y. Characterizing the micro lesion effect due to intraoperative microelectrode recording on motor symptoms in patients with Parkinson's Disease undergoing deep brain stimulation of the subthalamic nucleus. XXII congress of the ESSFN, Madrid, Spain 2016 

26. Kocabicak E, Aygun D, ​​Yildiz M O, Alptekin O, Temel Y (2016). Deep brain stimulation of the globus pallidus internus in patients with chorea dominant Huntington's Disease. XXII congress of the ESSFN, Madrid, Spain 2016 

27. Alptekin O, Kocabicak E, Temel Y (2016). Perioperative technical complications in deep brain stimulation surgeries. XXII congress of the ESSFN, Madrid, Spain 2016 

28. Yildiz O, Terzi M, Tugcu B, Alptekin O, Temel Y, Kocabicak E. Deep brain stimulation for Multiple Sclerosis related tremor clinical reports. II. International Conference on Deep Brain Stimulation Düsseldorf, Germany 2016 EP-35 

29. Kocabicak E, Aygun D, ​​Yildiz M O, Taskin O, Alptekin O, Temel Y (2016). Effects of Deep Brain Stimulation of the globus pallidus interna on Huntington's Disease at 1 year. II. International Conference on Deep Brain Stimulation Düsseldorf, Germany 2016 EP-34 

30. Kocabicak E, Ali Jahanshahi, Lisa Schonfeld, Sarah-Anna Hescham, Yasin Temel, Sonny K.H Tan. Deep brain stimulation of the rat subthalamic nucleus induced inhibition of median raphe serotonergic and dopaminergic neurotransmission. XXI Congress of the European Society for Stereotactic and Functional Neurosurgery (ESSFN), Final Programme, page: 7, Flash Oral Presentation no: 20 September 17-21, 2014, Maastricht, Netherlands.

31. Kocabicak E, Dursun Aygun, Kemal Paksoy, Musa Onar, Hatice Guz, Omer Boke, Murat Kurt, Murat Terzi, Onur Alptekin, Onur Yildiz, Yasin Temel. Microelectrode recording in subthalamic nucleus deep brain stimulation: advantage or loss of time? XXI Congress of the European Society for Stereotactic and Functional Neurosurgery (ESSFN), Final Programme, page: 4, Oral Presentation no: 18 September 17-21, 2014, Maastricht, Netherlands. 

32. Camlidag I, Kocabicak E, Sahin B, Jahanshahi A, Incesu L, Aygun D, ​​Yildiz O, Temel Y, Belet U. Volumetric analysis of the subthalamic and red nuclei based on magnetic resonance imaging in patients with Parkinson's disease. XXI Congress of the European Society for Stereotactic and Functional Neurosurgery (ESSFN), Final Programme, page: 22, Poster Presentation no: 17 September 17-21, 2014, Maastricht, Netherlands. 

33. Kocabicak E, Dursun Aygun, Murat Terzi, Musa Onar, Hatice Guz, Omer Boke, Yasin Temel. Deep brain stimulation in complex tremor. XXI Congress of the European Society for Stereotactic and Functional Neurosurgery (ESSFN), Final Programme, page: 5, Flash Oral Presentation no: 19 September 17-21, 2014, Maastricht, Netherlands. 

34. Kocabicak E, Musa Onar, Murat Terzi. Effect on postural stability of REM sleep behavioral disorder in Parkinson's disease. Dursun Aygun, 18th International Congress of Parkinson's Disease and Movement Disorders. Volume: 29 Pages: S226-S226 Supplement: 1 Meeting Abstract: 613. June 08-12, 2014, Stockholm, SWEDEN 

35. D. Aygun, Kocabicak E, M.K. Onar, K. Akpinar, H. Guz, O. Boke, M. Kurt. Patient selection for DBS in Parkinson's disease: Clinical experience with 33 consecutive patients. XX World Congress on Parkinson's Disease and Related Disorders. E-352, page:97, 8 -11 December 2013 Geneva, Switzerland. 

36. D. Aygun, Kocabicak E, M.K. Onar, K. Akpinar, H. Guz, O. Boke, M. Kurt. Effect of disease duration on preoperative levodopa responsiveness as a criterion for subthalamic nucleus deep brain stimulation in Parkinson's disease patients. The Movement Disorder Society's 17th International Congress of Parkinson's Disease and Movement Disorders. Vol. 28, Suppl 1,pp. S1–S464.No:1255. June 16-20, 2013 Sydney- Australia 

37. M.K. Onar, D. Aygun, Kocabicak E, H. Guz, C.K. Akpinar, O. Boke, M. Kurt. Stimulationrelated side effects in ten patients with Parkinson's disease treated by subtahalamic deep brain stimulation (DBS) The Movement Disorder Society's 17th International Congress of Parkinson's Disease and Movement Disorders. Vol. 28, Suppl 1, pp. S1–S464.No:1275 June 16-20, 2013 Sydney- Australia 

38. M.K. Onar, D. Aygun, K. Akpinar, Kocabicak E, O. Boke, H. Guz, M. Kurt. Dopamine dysregulation syndrome after deep brain stimulation (DBS): A case report. The Movement Disorder Society's 17th International Congress of Parkinson's Disease and Movement Disorders. Vol. 28, Suppl 1, pp. S1–S464.No:1276, June 16-20, 2013 Sydney- Australia 

39. Kocabicak E, Aygun D, ​​Ozaydin I, Jahanshahi A, Onar M, Boke O, Kurt M, Guz H, Terzi M, Alptekin O, Yildiz O,Temel Y. Does probe's eye subthalamic nucleus length on T2W MRI correspond with microelectrode recording in patients with deep brain stimulation for advanced Parkinson's disease? 15th World Congress of Neurosurgery (WFNS), Program Book, FA1935, page: 312, September 8-13, 2013, Seoul, Korea

40. Kocabicak E, Dursun Aygun, Hatice Guz, Murat Kurt, Binnur Sarıhasan, Yasin Temel. Conversion of local anesthesia guided deep brain stimulation of the subthalamic nucleus to general anesthesia. XX Congress of the European Society for Stereotactic and Functional Neurosurgery (ESSFN), P 80, page: 142 September 26-29, 2012, Lisbon, Portugal. 

41. Kocabicak E, Murat Terzi, Yasin Temel. Targeting thalamic tremor cells in deep brain stimulation for Multiple Sclerosis induced complex tremor. XX Congress of the European Society for Stereotactic and Functional Neurosurgery (ESSFN), P 81, page: 142 September 26-29, 2012, Lisbon, Portugal. 

42. Kocabicak E, Lee Wei Lim, Harry W.M. Steinbusch, Yasin Temel. Deep brain stimulation of the ventromedial prefrontal cortex induced neuronal changes in the dorsal raphe nucleus of rats. EANS 2011 14th European Congress of Neurosurgery program book, page: 107, October 9-11, 2011 Rome-Italy 

43. Kocabicak E, Cokluk C, Aydin K. Geriatric Epidural Haematoma: Case Report and Review of The Literature. 15th Euroacadimia MultidisciplinariaNeurotraumatologica Congress (EMN) Final Program, P-07 page:20, May 6-9, 2010, Antalya, Turkey 

And More

Personal Information

Name Surname : Mustafa SEZER
Place of Birth - Year :    Balıkesir - 1969
Academic Title : Op. Dr.
Foreign Language : English

Education

Ankara Numune Hospital 1998-2003
Osmangazi Faculty of Medicine 1994
Work Experience

Private Century Hospital 2000-... 
Ankara Numune Hospital Brain and Neurosurgery Clinic 1998-2003
Kocaeli Ulaşlı Health Centre 1996-1998
Siirt State Hospital Emergency Service 1994-1996

PROFESSIONAL EXPERIENCE

2019-present: Department of Neurosurgery, Florence Nightingale Hospitals affiliated to Demiroglu Bilim University Medical Faculty, Istanbul/Turkey. Associate Professor

2017-2019: Department of Neurosurgery, Liv Hospital Ulus affiliated to Istinye University Medical Faculty, Istanbul/Turkey. Associate Professor

2016-2017: Department of Neurosurgery, Liv Hospital Ulus affiliated to Istinye University Medical Faculty, Istanbul/Turkey. Assistant Professor

2015-present: Department of Neurosurgery, Liv Hospital Ulus, Istanbul/Turkey. Attending Neurosurgeon

2013-2015: Department of Neurosurgery, GOP Taksim Training and Research Hospital, Istanbul/Turkey. Attending Neurosurgeon

2006-2012: Department of Neurosurgery, Istanbul School of Medicine, Istanbul University, Istanbul/Turkey. Resident

EDUCATION 

October 2017-March 2018: Clinical Fellowship on Stereotactic and Functional Neurosurgery, Department of Neurosurgery, Hannover Medical School, Hannover/Germany (Professor Joachim K. Krauss M.D, Ph.D)

January-April 2010: Clinical Fellowship on Microsurgery of Peripheral Nerves and Brachial Plexus, Division of Peripheral Nerve Reconstruction, Department of Neurosurgery, Tel Aviv Sourasky Medical Center, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv/Israel (Professor Shimon Rochkind M.D, Ph.D)

2006-2012: Resident at Department of Neurosurgery, Istanbul School of Medicine, Istanbul University, Istanbul/Turkey

2005-2006: Resident at Department of Anatomy, Cerrahpasa School of Medicine, Istanbul University, Istanbul/Turkey

1999-2005: Istanbul School of Medicine, Istanbul University, Istanbul/Turkey GPA: 3.17/4.00

1991-1999: Istanbul Erkek Lisesi (High School), Istanbul/Turkey GPA: 4.47 / 5.00

Experience

Hospitalpark Darıca Hospital

Sultanbeyli State Hospital

Yesilyurt State Hospital

Edirne Health Center No. 4

Education

Selçuk University Faculty of Medicine (1989)

Istanbul Göztepe Training and Research Hospital

Vocational Trainings, Courses and Conferences Attended

Marmara University Istanbul Pediatric Orthopedic Meetings "Sipina Bifida" Symposium

Turkish Neurosurgery Association Cervical Disc Herniation Course

Turkish Neurosurgery Association "Spinal Surgery and Peripheral Nerve Surgery" Training Course

Turkish Neurosurgery Association "Cerebrovascular Surgery" Training Course

Turkish Neurosurgery Association "Head Traumas, Pain Management and Functional Neurosurgery" Training Course

TCDD "Preventive Medicine" Course

Turkish Neurosurgery Association "12th Scientific Congress" Antalya

Turkish Neurosurgery Association "13th Scientific Congress" Istanbul

Turkish Neurosurgery Association Course on "Tumors"

Professional Memberships

Turkish Neurosurgery Association

Turkish Medical Association

Education & Expertise

1996 to 2000 | Dicle University – Medical Education

Professional Experience

2001 to 2006 | Diyarbakır State Hospital – Neurology Specialist

2006 to 2009 | Düzce Atatürk State Hospital – Neurology Specialist

2009 to 2013 | Düzce University – Associate Professor of Neurology

2013 to 2016 | Düzce University – Associate Professor of Neurology

2017 to 2024 | Pendik Private Century Hospital – Associate Professor of Neurology

2024 to Present | VM Medical Park Pendik Hospital – Associate Professor of Neurology

Courses & Certifications

June, 2012 | Trainer Training Course

February, 2010 | Trainer Training Course

March, 2011 | Sleep Medicine Certification Program Preparation Course

December, 2012 | Sleep Disorders Diagnosis and Treatment Course

DBS Application Training and Course – Dubai

Professional Memberships

Turkish Medical Association

Turkish Neurology Association

Turkish Sleep Medicine Association

Awards & Recognitions

2014 | Düzce University Rectorship – Publication Success Incentive Award

Experience

• -Head of the Department of Functional Neurosurgery and Radiosurgery at Ruber International Hospital since 2005 .
• - Neurosurgeon in the Radiosurgery Department of Ruber International Hospital since 1993 .
• -Work experience at Puerta de Hierro Clinic, Madrid (1985–1989) .

Scientific and teaching activities

• -180 publications in national and international medical journals.
• 60 articles in leading international journals with high impact factor.
• - Participation in 230 scientific conferences as a speaker, including 100 invited presentations at international symposia.
• -Author : 3 published books and 22 chapters in scientific papers.
• - Honorary Professor of the Faculty of Medicine of the Autonomous University of Madrid .

Internships in international centers

• - La Timone Hospital, Marseille (France) – 2000, 2010, 2015.
• -Karolinska Hospital, Stockholm (Sweden) – 1993, 1996.
• - Birmingham Hospital, UK – 1987

Membership in scientific societies

• - Member of the International Society of Stereotactic Radiosurgery (ISRS) , is a member of the Executive Council and the Educational Committee .
• - Member of the Congress of Neurological Surgeons of the United States and the American Association of Neurological Surgeons .
• -Member of the Royal Academy of Medicine of Asturias, Spain .

Languages of practice

• -Spanish
• -English
• -French

Pathologies

-Benign brain tumors: meningiomas and neuromas:

-Cerebral vascular malformations:

-Obsessive-compulsive disorder treatment operations:

-Operations to combat nervous anorexia:

Publications

2023 | Stereotactic radiosurgery for Kuss grade IV vestibular schwannoma in patients ≥ 65 years: a multi-institutional retrospective study Acta Neurochirurgica 165: 211–220,

2022 | Stereotactic radiosurgery for Kues grade IV vestibular schwannoma in young patients: a multi-institutional study Journal of Neuro-Oncology 160: 201–208.

2022 | Stereotactic radiosurgery versus active surveillance for asymptomatic, parafalcine, and parasagittal meningiomas: a matched cohort analysis from the IMPASSE Neurosurgery 90:750–757

2022| Active surveillance versus stereotactic radiosurgery for the treatment of patients with incident frontobasal meningioma - A subanalysis of the IMPASSE Cancers (Basel) trial. Mar 3;14(5):1300.

2022| Gamma Knife Outcomes and Recommendations and Complications: Patai fond Kuala Lumpur

2022| Radiosurgery for Mental Disorders LGKA Marsella

2022| The Role of SRS in Anorexia Nervosa ISRS Milan

2022| Expanding the indications for gamma knife radiosurgery Neuroonc and Rs Symp Malasia

2022 | Pituitary Adenoma: Conservative in Surgical Abortion Simp CUF Lisbo

Awards and certificates

2019|National Medical Prize XXI in the field of neurosurgery.

2018 | Editorial Board Member, American Journal of Psychiatry and Neurology

2015 | Factory Award torn away from the International Society of Stereotactic and Radiosurgery

2012 | Correspondent of the Real Medical Academy of Asturias.

Assoc. Prof. Ozdogan, M.D., Ph.D., completed his education at Yeditepe University Health Sciences Institute in the Molecular Medicine Doctorate Program under Prof. Dr. Turgay İsbir, and he also studied at Saint Louis University in Arkansas, USA, with Prof. Dr. M. Gazi Yasargil. He pursued a Clinical Fellowship in Brain and Nerve Surgery at Yeditepe University Hospital, guided by Prof. Dr. Yasargil and Prof. Dr. Uğur Türe. Additionally, he underwent specialization training at Ufuk University Faculty of Medicine, the Faculty of Medicine at Gazi University, and completed his secondary education at İçel Anatolian High School.

Professionally, he has held various positions, including Faculty Member in the Department of Neurosurgery at Haliç University, and Associate Professor at Private Adatip Istanbul Hospital and Biruni University Hospital. He has also served as an Associate Professor at S.B.U. Kartal, Sancaktepe, and Istanbul Training and Research Hospitals, and worked as a Chief Assistant at S.B.U. Gaziosmanpaşa Taksim and Kartal Training and Research Hospitals. His earlier roles include Specialist Doctor at S.B.U. Baltalimanı Bone Diseases Hospital and Mus State Hospital, as well as Clinical Fellow at Yeditepe University Faculty of Medicine Hospital.

Assoc. Prof. Özdoğan is a member of several professional associations, including the Turkish Neurosurgery Association, Turkish Spine Association, and the Turkish Neurosurgery Society’s Neuroanatomy, Neurovascular, and Neurooncology Groups. He is also affiliated with the European Association of Neurosurgical Societies.

Education

2019

Istanbul Faculty of Medicine, Electroneurophysiology

2005

Istanbul University Cerrahpasa Faculty of Medicine, Neurology

1998

Istanbul University Cerrahpasa, Faculty of Medicine

Experience

2017 - 2019

Private Adatip Kurtkoy Hospital

2016

TND – Schering-Plough Proceedings of the Year Awards

2015 - 2017

Istanbul Yeni Yüzyıl University Private Gaziosmanpaşa Hospital

2015 - 2015

Şişli Hamidiye Etfal Training and Research Hospital

2005 - 2014

Private Avicenna Hope Hospital

2015 – 2019 Istanbul University Cerrahpasa Faculty of Medicine

2019 – Medipol University Pendik Hospital

Publications

1- Yüz Ağrılarında Trigeminal SEP Uygulaması ; Yüksek Lisans Tezi

2- Glial Tümörlerde P53 , PTEN ve EGRF Pozitifliğinin İmmunohistokimyasal ; Uzmanlık Tezi

3- Two siblings with homocystinuria presenting with dystonia and parkinsonism

4- Lack of association between IL-1ß/? gene polymorphisms and temporal lobe epilepsy with hippocampal sclerosis

5- Psychogenic movement disorders in two children

6- Temporal Lob Epilepsi ve Hippokampal Sklerozlu Hastalarda İnterlökin 1-ß ve İnterlökin 1-? Gen Polimorfizminin Analizi

7- Hippokampal Skleroza Bağlı Mesial Temporal Lob Epilepsisi İle İnterlökin 1-ß ve İnterlökin 1-? Gen Polimorfizmi İlişkisinin Araştırılması

Trustworthy, attentive, successful neurosurgeon with over 34 years of experience, high rate of success and exceptional surgical skills, providing quality neurological service for patients, successfully treating over thousands of patients suffering from many severe, complex conditions of the brain, spine and the nerves. 

Experienced in performing treatment modalities like micro neurosurgery, endoscopic skull base surgery, endoscopic third ventriculostomy, minimally invasive spine surgery and percutaneous spine surgery. Keen on performing clinical research and attending national and international medical conferences to stay abreast of new technologies in the field. Compassionate and detail-oriented with excellent communication skills. Expertise in healthcare, education and program management. Adept at developing and implementing forward-thinking strategies to enhance patient outcomes and collective knowledge in the field. Desiring to bring skills and success. Focused on working closely with other medical professionals and following up with patients. Well-versed at emergency procedures and fast and accurate sanitation.

Work History

2020-01 – Current - Asst. Prof. Neurosurgeon

Istanbul Medipol University, Health Care Practice and Research Center Pendik Hospital

• He successfully treated and followed patients with cerebral hemorrhage, brain and spinal cord tumors, and patients with hydrocephalus.

• He performed transnasal pituitary surgeries with success.

• Also, many cervical lumbar and thoracic disc patients were successfully treated, and disc prosthesis were applied to some of them.

• He re-operated a degenerative spine patient who had been operated on before at another center and the patient regained his health.

• He also successfully treated patients with premature neonatal intracerebral hemorrhage.

2019-08 – 2020-01 - Neurosurgeon

Freelancer, Istanbul, Turkey

• Operated on patients' brains, spines and peripheral nerves to correct deformities, repair injuries, prevent and treat diseases and improve patients' motor functions. Performed successful operations for complex, advanced and complicated disease of the brain and spine some of which were operated unsuccessfully at other medical centers by different neurosurgeons.

• Offered advanced knowledge, leadership abilities and technical assistance with complex surgical cases.

• Maintained admitting privileges at local hospitals and provided quality follow-up care.

• Educated patients on recovery methods and times.

• Designed treatment plans for patients.

• Thoroughly assessed patients to identify medical condition and level of surgical risk.

• Founded a spinal surgery group with orthopedic surgeons and treated very advanced and severe vertebra deformities, spine abnormalities, scoliosis.

2018-12 - 2019-08 - Neurosurgeon

Alkafeel Super Speciality Hospital, Karbala, Iraq

• Conducted up to 5 operations per month to correct deformities in neurological and spinal systems, repair traumas, and treat diseases of different areas. Performed successful operations (success rate 100 percent : 90-95) for severe, complex and advanced diseases of the brain, spine and nerves in adults and children. (Cerebral intrinsic and extrinsic tumor surgery, posterior fossa surgery, spontaneous and traumatic intracranial hematomas, Interhemispheric 3th ventricle and lateral ventricle surgery, pontocerebellar angle tumor surgery, spinal instrumentation and fusion surgery, microdiscectomy cervical, thoracic, lumbar, pediatric cranial and spine anomaly surgery). Followed the patients postoperatively.

• Educated patients on recovery methods and times.

• Thoroughly assessed patients to identify medical condition and level of surgical risk.

• Performed emergency surgeries.

• Examined 900 patients in total in the outpatient clinic and gave medical treatments to them when necessary.

2015-10 - 2018-11 - Neurosurgeon

Medistate Kavacık Hospital, Istanbul, Turkey

• Operated on patients' brains, spines and peripheral nerves to correct deformities, repair injuries, prevent and treat different advanced, complex severe diseases and improve patients' motor functions.

• Conducted up to operations per month to correct deformities in neurological and spinal systems, repair traumas, restore partial or full functionality and prevent and treat diseases of different areas. 

• Performed successful operations (success rate percent : 95) for severe, complex and advanced diseases of the brain , spine and nerves in adults and children.(Brain tumor, arachnoid cyst, intracerebral hematoma, spinal stenosis, hydrocephalus, myelomeningocele).Followed the patients postoperatively. 

• Educated patients on recovery methods and times Thoroughly assessed patients to identify medical condition and level of surgical risk.

• Performed emergency surgeries (intracerebral hematoma, intracerebral abscess).

• Examined 850 patients in total in the outpatient clinic and gave medical treatment to them when necessary.

1994-03 - 2015-09 - Neurosurgeon

Ankara Training and Research Hospital, Ankara, Turkey

• Supervised trainees, medical students, residents and fellows to help each achieve proficiency in field.

• Conducted up to 20 operations per month to correct deformities in neurological and spinal systems, repair traumas, restore partial or full functionality and prevent and treat diseases of different areas. Performed successful operations (success rate: %90) for severe, complex and advanced diseases of the brain, spine and nerves in adults and children. (Skull base surgery, extended trans base approach, orbit zygomatic approach, presigmoid approach, orbital approaches, transcranial and lateral orbitotomy, Endoscopic transsphenoidal pituitary surgery, CSF leakage surgery, endoscopic, microscopic and transsphenoidal, transcranial. Endoscopic third ventriculostomy and surgery of multiloculated hydrocephalus and pediatric neurosurgery. Cerebral intrinsic and extrinsic tumor surgery, posterior fossa surgery. Brain aneurysm, AVM and cavernoma surgery.

• Spontaneous and traumatic intracranial hematomas. Hemifacial spasm and trigeminal neuralgia surgery (microsurgical decompression) Interhemispheric 3th ventricle and lateral ventricle surgery. Pineal area surgery. Pontocerebellar angle tumor surgery.

• Foreman magnum tumors surgery. Surgery of hydrocephaly, Syringomyelia and craniovertebral animalia).Followed the patients postoperatively.

• Educated patients on recovery methods and times Thoroughly assessed patients to identify medical condition and level of surgical risk.

• Performed emergency surgeries (Epidural, subdural and intracerebral hematoma, vertebra fracture).

• Examined 500-700 patients per day in the outpatient clinic and gave medical treatment to them when necessary. Examined patients in the emergency service.

• Designed treatment plans for patients.

• Offered advanced knowledge, leadership abilities and technical assistance with complex surgical cases.

• Led and oversaw 15 medical personnel in operating room setting to perform surgeries.

• Led and oversaw medical personnel in operating room setting to perform surgeries.

Education

1982-09 - 1988-08

M.D.: Medicine And (Pre-Medicine)

Ankara University Medical School - Ankara

General Medicine Training for 6 years. Graduated with a high GPA.

1988-11 - 1994-05

Specialist Neurosurgery: Neuroscience

University of Health Sciences - Ankara

6 years of neurosurgery training.

• My thesis was on brain abscess and their clinical and laboratory evaluations

1995-05 - 1995-07

Neuroscience

The Institute of Neurological Sciences and Psychiatry.

Ankara

I attended the course for microsurgery at University of Hacettepe Institute of Neurological Sciences and Psychiatry.

1998-04 - 2019-05

Observer Doctor: Neuroscience

Department of Neurosurgery, MSU - Ann Arbour, 

Michigan USA

2012-05 - 2012-05

Neuro endoscopy: Neuroscience

Ghent University - Ghent, Belgium

International endoscopic neurosurgery workshop, 

Ghent, Belgium

I attended the workshop for endoscopic skull base operations the and Neuro endoscopic third ventriculostomy at University of Ghent Hospital

Skills

Micro neurosurgery - Excellent

Neuro endoscopy - Excellent

Cranial base endoscopy - Excellent

Minimal invasive surgery - Excellent

Percutaneous spinal surgery - Excellent

Neuronavigation – Excellent

Certifications

1995-04 Microsurgery

2012-05 Endoscopy

Languages

Turkish - Native

English - Advanced

Arabic - Novice

Affiliations

Turkish Neurosurgical Society

Turkish Medical Association

Accomplishments

• Trained team of staff nurses in medical office procedures to ensure consistent quality of care.

• Published 17 articles in national and international reviews and presented papers in medical congresses.

Interests and operations I perform

Vascular diseases of brain

Endoscopic hypophysis surgery

Tumors of brain, spine and medulla spinalis surgery

Endoscopic brain ventricle surgery

Endoscopic third ventriculostomy 

Traumas of brain and spine

Cervical, thoracic and lumbar disc hernias and narrow 

canal disease surgery

Spine instrumentation and fusion surgery

Baclofen pump and neurostimulators insertions

Hydrocephalus surgery

Congenital diseases of the brain and spine (pediatric 

neurosurgery)

Peripheral nerve surgery

Experience

2019 – 2019

• University of Insubria, Varese, Italy, 

Insubria University Faculty of Medicine

2015

• MERSİN UNIVERSITY/FACULTY OF MEDICINE, DOCTOR, LECTURER

2013 – 2015

• ANKARA PRIVATE ACIBADEM HOSPITAL

2010 – 2012

• DIYARBAKIR TRAINING AND RESEARCH HOSPITAL,

2002 – 2003

• AYDIN 1ST PRIVATE TRAINING BATTALION
•  

Education

2010

• ANKARA UNIVERSITY FACULTY OF MEDICINE, BRAIN AND SURGERY SPECIALIST

1992

• GAZI UNIVERSITY, FACULTY OF MEDICINE

PROFESSIONAL EXPERIENCE

2011-2012
Erzurum Koprukoyu State Hospital
Department: General Medicine

2012-2017
Istanbul University Cerrahpaşa Medical Faculty
Department: Internal Medicine

06/2017-10/2017
Istanbul Gaziosmanpasa Taksim Training and Research Hospital
Department: Internal Medicine

10/2017-11/2018
Istanbul University Istanbul Medical Faculty
Department: Allergy and Immunology Fellowship

2018/2022
Istanbul University Oncology Institute
Department: Medical Oncology Fellowship

2022-2023
Tekirdag City Hospital
Department: Medical Oncology Specialist

2023-present
Istanbul Medipol University Medipol Bahcelievler Private Hospital
Department: Medical Oncology Assoc. Prof.

EDUCATION

2005-2011
Medical Education
Sivas Cumhuriyet University Medical Faculty, Sivas, Turkey

2012-2017
Internal Medicine
Istanbul University Cerrahpaşa Medical Faculty, Department of Internal Medicine, Istanbul, Turkey

2017-2018
Allergy-Immunology Fellowship
Istanbul University Istanbul Medical Faculty
Department of Internal Medicine, Division of Allergy and Immunology, Istanbul, Turkey

2018-2022
Medical Oncology Fellowship
Istanbul University Oncology Institute, Department of Medical Oncology, Istanbul, Turkey

2022
ESMO Board Certification in Medical Oncology
10th September 2022 in Paris, France.

2023
Medical Oncology Assoc. Prof.
Istanbul Medipol University Department of Medical Oncology, Istanbul, Turkey

INTERNATIONAL CLINICAL TRIALS:

1. Astefania - ROCHE

• Title: A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy
• Role: Subinvestigator

2. PFİZER

• Title: A Study Of Lorlatinib Versus Crizotinib In First-Line Treatment Of Patients With ALK-Positive NSCLC
• Role: Subinvestigator

3. RECITE - AMGEN

• Title: Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancreatic, or Colorectal Cancer
• Role: Subinvestigator

4. NAVIGATE - BAYER

• Title: A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors
• Role: Subinvestigator

5. RUBY - Tesaro (PRA)

• Title: A Phase 3, Randomized, Double-blind, Multicenter Study of Dostarlimab (TSR-042) Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Patients With Recurrent or Primary Advanced Endometrial Cancer
• Role: Subinvestigator

6. ENGOT-ov43/GOG-3036 - MSD

• Title: Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK001/ENGOT-ov43/GOG-3036)
• Role: Subinvestigator

7. ASTRA ZENECA

• Title: To Study Clinical Effectiveness and Safety of Olaparib Monotherapy in Metastatic Breast Cancer Patients.
• Role: Subinvestigator

8. ROSY-O - ASTRA ZENECA

• Title: Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib
• Role: Subinvestigator
•  

INTERNATIONAL PUBLICATIONS

I. Published journal articles indexed by SCI, SSCI, and AHCI

Weekly Paclitaxel in Classic Kaposi Sarcoma

• Authors: Paksoy, N., Khanmammadov, N., Doğan, İ., Ferhatoğlu, F., Ahmed, M. A., Karaman, S., & Aydiner, A.
• Journal: Medicine, 102(5)

Carboplatin Desensitization in Ovarian Carcinoma

• Authors: Paksoy, N., Khanmammadov, N., Doğan, İ., Ferhatoğlu, F., Yildiz, A., Ak, N., & Aydiner, A.
• Journal: Medicine, 101(45), e31726

High-Dose Chemotherapy for Ewing’s Sarcoma

• Authors: Paksoy, N., Ferhatoglu, F., Dogan, İ., Khanmammadov, N., Celik, A. I., Gulbas, Z., & Başaran, M.
• Journal: Medicine, 101(49), e32213

Multidrug Refractory TFE3(+) Renal Cell Carcinoma

• Authors: Paksoy, Nail, et al.
• Journal: Journal of Oncology Pharmacy Practice, 2022, 28.1: 215-221

Crizotinib Efficacy in NSCLC with MET Alterations

• Authors: Gürbüz, M., Kiliçkap, S., Bilici, A., Karadurmuş, N., Sezer, A., Şendur, M. A. N., ... & Demirkazik, A.
• Journal: Medicine, 101(50), e32368

Clinicopathological Features in ALK Mutant NSCLC

• Authors: Dogan, I., Gurbuz, M., Paksoy, N., Ferhatoglu, F., Vatansever, S., Saip, P., ... & Aydiner, A.
• Journal: Medicine, 101(34)

PSMA-Based Tumor Burden in Prostate Cancer

• Authors: HAS SIMSEK, Duygu, et al.
• Journal: Annals of Nuclear Medicine, 2021, 35.6: 680-690

Atezolizumab in Metastatic Urothelial Carcinoma

• Authors: TURAL, Deniz, et al.
• Journal: European Urology Focus, 2021, 7.5: 1061-1066

Pulmonary Sarcomatoid Carcinoma

• Authors: FERHATOGLU, Ferhat, et al.
• Journal: Oncology Research and Treatment, 2021, 44.11: 590-601

Prognostic Factors in Atezolizumab-Treated Urothelial Carcinoma

• Authors: TURAL, Deniz, et al.
• Journal: International Journal of Clinical Oncology, 2021, 26.8: 1506-1513

Atezolizumab with Chemotherapy in Small Cell Lung Cancer

• Authors: GÜRBÜZ, Mustafa, et al.
• Journal: Journal of Cancer Research and Clinical Oncology, 2022, 1-9

FOLFIRINOX vs. Gemcitabine + Nab-Paclitaxel in Pancreatic Cancer

• Authors: AY, Seval, et al.
• Journal: Journal of Chemotherapy, 2022, 1-7

Trastuzumab Emtansine in Older HER2-Positive Breast Cancer Patients

• Authors: CIL, Ibrahim, et al.
• Journal: Tumori Journal, 2022, 108.1: 19-25

Real-Life Efficacy of Osimertinib in Advanced NSCLC

• Authors: HIZAL, Mutlu, et al.
• Journal: Journal of Cancer Research and Clinical Oncology, 2022, 148.6: 1501-1508

ALK-Positive Cells Percentage and Alectinib Efficacy

• Authors: Hizal, M., Bilgin, B., Paksoy, N., Atcı, M. M., Kahraman, S., Kılıçkap, S., ... & Şendur, M. A. N.
• Journal: Journal of Cancer Research and Clinical Oncology, 149(8), 4141-4148

Real-World Data on Alectinib in ALK-Positive NSCLC

• Authors: Hizal, M., Bilgin, B., Paksoy, N., Kılıçkap, S., Atcı, M. M., Kahraman, S., ... & Şendur, M. A. N.
• Journal: Future Oncology, 18(23), 2573-2582

Prognostic Factors in Metastatic RCC with T790M Mutation

• Authors: Dogan, I., Iribas, A., Paksoy, N., Vatansever, S., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

FLOT Regimen in Metastatic Gastric Cancer

• Authors: Tastekin, D., Paksoy, N., Dogan, I., Ferhatoglu, F., Khanmammadov, N., Bozbey, H. U., & Karabulut, S.
• Journal: Journal of Cancer Research and Therapeutics

Desensitization Protocol in Lenalidomide Hypersensitivity Reactions

• Authors: DEMIR, Semra, et al.
• Journal: Annals of Allergy, Asthma & Immunology, 2019, 123.4: 394-397

Factors Associated with Diagnostic Skin Test Positivity in PPI Hypersensitivity

• Authors: ÖZDEMIR, Seçil Kepil, et al.
• Journal: Allergy, 2019, 74.6: 1187-1190

Efficacy of Capecitabine and Temozolomide in Neuroendocrine Tumors

• Authors: Ünal, Ç., Azizy, A., Karabulut, S., Taştekin, D., Akyıldız, A., Yaşar, S., ... & Sağlam, S.
• Journal: The Oncologist, oyad257

Subsequent Treatments in Hormone-Positive Breast Cancer Progression

• Authors: Karacin, C., Oksuzoglu, B., Demirci, A., Keskinkılıç, M., Baytemür, N. K., Yılmaz, F., ... & Hacıbekiroğlu, İ.
• Journal: BMC cancer, 23(1), 192

Termination of Trastuzumab in HER2-Positive Metastatic Breast Cancer

• Authors: Dogan, I., Aydin, E., Khanmammadov, N., Paksoy, N., Saip, P., & Aydiner, A.
• Journal: Scientific Reports, 13(1), 8779

Long-term Outcomes and Predictors of Recurrence in Node-Negative Early Stage Breast Cancer

• Authors: Dogan, I., Aydin, E., Khanmammadov, N., Paksoy, N., Ferhatoğlu, F., Ak, N., ... & Aydiner, A.
• Journal: Journal of Cancer Research and Clinical Oncology, 1-9

Prognostic Factors Influencing PFS in HER2-Positive Metastatic Breast Cancer

• Authors: Doğan, İ., Paksoy, N., Ak, N., Vatansever, S., Saip, P., & Aydıner, A.
• Journal: European Journal of Breast Health, 19(2), 128

Treatment Efficacy of Ribociclib or Palbociclib plus Letrozole in Metastatic Breast Cancer

• Authors: Kahraman, S., Erul, E., Seyyar, M., Gumusay, O., Bayram, E., Demirel, B. C., ... & Nahit Sendur, M. A.
• Journal: Future Oncology, 19(10), 727-736

Efficacy and Safety of Sorafenib in Adult Metastatic Osteosarcoma Patients

• Authors: Dogan, I., Paksoy, N., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

Single-Agent Temozolomide as Salvage Therapy in Heavily Pretreated Metastatic Sarcoma Patients

• Authors: Dogan, I., Paksoy, N., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

Outcomes and Prognostic Factors in Metastatic Renal Cell Carcinoma with Brain Metastases

• Authors: Dogan, I., Iribas, A., Paksoy, N., Vatansever, S., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

FLOT Regimen in First-Line Treatment of Metastatic Gastric Cancer

• Authors: Tastekin, D., Paksoy, N., Dogan, I., Ferhatoglu, F., Khanmammadov, N., Bozbey, H. U., & Karabulut, S.
• Journal: Journal of Cancer Research and Therapeutics

Prognostic Factors of Perioperative FLOT Regimen in Operable Gastric Cancer

• Authors: Erol, C., Sakin, A., Basoglu, T., Ozden, E., Cabuk, D., Dogan, M., ... & Sendur, M. A. N.
• Journal: [Not specified]

Efficacy and Outcomes of Systemic Chemotherapy in Posttransplant Kaposi Sarcoma

• Authors: Khanmammadov, N., Paksoy, N., Doğan, I., Ferhatoğlu, F., Saip, P., & Aydiner, A.
• Journal: Medicine, 102(39), e35383

Comparison of Second-Line Treatments in Metastatic Renal Cell Carcinoma

• Authors: Pehlivan, M., Paksoy, N., Aydin, E., Basaran, M., & Ekenel, M.
• Journal: Medicine, 102(41), e35245

Toxicity Management and Effectiveness of Regorafenib in Advance GIST Patients: A Real-world Study - Authors: Paksoy, N., Ferhatoğlu, F., Doğan, İ., Khanmammadov, N., Bozbey, H. U., Karabulut, S., & Taştekin, D. - Journal: TURKISH JOURNAL OF ONCOLOGY, 1(1)

Demographic and Clinical Features and Factors Associated with Survival in Patients with Primary Glomerulonephritis: Single Tertiary Center Experience - Authors: Paksoy, N., Trabulus, S., Seyahi, N., & Altiparmak, M. R. - Journal: Namik Kemal Tip Dergisi, 11(1)

Efficacy of Sorafenib in Symptomatic Patients with Pretreated Progressive Desmoid Tumors - Authors: Paksoy, N., Ferhatoglu, F., Dogan, I., Ak, N., Pehlivan, M., Ekenel, M., & Basaran, M.

Nodal Response to Neoadjuvant Chemotherapy is a Better Predictive Factor of Survival Than Miller-Payne Scoring in Breast Cancer - Authors: Ak, Naziye, et al. - Journal: Journal of Oncological Sciences, 7.2: 42-49

Evaluation of Prognostic and Predictive Values of Hemogram Parameters in Patients with Advanced Stage Ovarian Carcinoma - Authors: Ak, Naziye, et al. - Journal: Turkish Journal of Oncology/Türk Onkoloji Dergisi, 2021, 36.4

Identifying Risk Factors Associated with Survival and Drug-Related Toxicities in Imatinib-Resistant Gastrointestinal Stromal Tumor (GIST) Patients Treated with Sunitinib - Authors: Ferhatoglu, F., Karabulut, S., Paksoy, N., & Tastekin, D.

Real-life Outcomes of ROS1 Fusion-positive Metastatic Lung Cancer Patients who were Treated with Crizotinib - Authors: Dogan, İ., Khanmammadov, N., Paksoy, N., Ferhatoglu, F., Aydın, E., Vatansever, S., & Aydine, A. - Journal: TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY

Predictors of the acquisition of T790M mutation in EGFR-mutant metastatic lung cancer patients who were treated with EGFR inhibitors - Authors: Dogan, I., Khanmammadov, N., Paksoy, N., Vatansever, S., Saip, P., & Aydıner, A. - Journal: Eurasian Journal of Pulmonology

Laterality of Adrenal Gland Metastasis in Lung Cancer: Results of a Comparative Study - Authors: Ferhatoglu, F., Gagatay, T., Okumus, G., Aydiner, A., Paksoy, N., Ak, N., ... & Saip, P. - Journal: Eurasian Journal of Medical Investigation, 7(2)

Poor Risk Factors Affecting Cancer Patients Infected with Covid-19: A Retrospective Comparative Study from a Pandemic Hospital - Authors: Ferhatoglu, F., Kapağan, T., Paksoy, N., Ak, N., Medetalibeyoğlu, A., Şenkal, N., ... & Vatansever, S. - Journal: Turk Onkoloji Dergisi, 38(1)

Systemic Treatment Outcomes of Progressive Medullary Thyroid Carcinoma from the Registries of a Tertiary Cancer Center - Authors: Ferhatoglu, F., Paksoy, N., & Başaran, M. - Journal: Namik Kemal Tip Dergisi, 10(4)

Evaluation of clinical features and risk factors related to late recurrence (> 5 years) in patients with breast cancer - Authors: Ferhatoglu, F., Aydiner, A., & Paksoy, N. - Journal: Journal of Surgery & Medicine (JOSAM), 6(12)

Assessing the Clinical Impact of Lutetium-177 DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) on Metastatic Neuroendocrine Tumors: A Multicenter Real-World Data from Türkiye

Thesis:

Istanbul University Cerrahpaşa Medical Faculty, Internal Medicine Department PAKSOY, Nail. Demographical, clinical characteristics and survival factors in patients withprimary glomerulonephritis: Cerrahpasa Medical Faculty Experience. (2016)

International Refereed Congress / Symposium Publications in Proceedings (ASCO/ESMO Abstracts)

Prognostic factors influencing progression-free survival in HER2 positive metastatic breast cancer patients who treated with lapatinib and capecitabine combination

• Authors: Dogan, I., Paksoy, N., Ak, N., Vatansever, S., Saip, P., & Aydiner, A. (2022)

Efficacy of regorafenib and 5-fluorouracil-based rechallenge treatment in the third-line treatment of metastatic colorectal cancer: A Turkish oncology group study

• Authors: Şenocak Taşçi, E., Oyan, B., Sonmez, O., Mutlu, A. U., Atcı, M. M., Oner, I., ... & Gulmez, A. (2022)

Long-term outcomes and predictors of recurrence in patients with early-stage node-negative breast cancer

• Authors: Dogan, I., Aydin, E., Paksoy, N., Ferhatoglu, F., Ak, N., Ibis, K., ... & Aydiner, A. (2021)

Efficacy of temozolomide in pretreated patients with metastatic sarcoma

• Authors: Paksoy, N., Dogan, I., Ekenel, M., & Basaran, M. (2021)

Efficacy of sorafenib in symptomatic patients with pretreated progressive desmoid tumors

• Authors: Ferhatoglu, F., Paksoy, N., Dogan, I., Ak, N., Pehlivan, M., Ekenel, M., & Basaran, M. (2021)

Efficacy of sorafenib in heavily pretreated adult patients with metastatic osteosarcoma

• Authors: Paksoy, N., Dogan, I., Ekenel, M., & Basaran, M. (2021)

Outcomes and prognostic factors in metastatic renal cell carcinoma patients with brain metastases

• Authors: Dogan, İ., Iribas, A., Paksoy, N., Ekenel, M., Vatansever, S., & Basaran, M. (2021)

Association of response to first-line chemotherapy with the efficacy of atezolizumab in patients with metastatic urothelial carcinoma

• Authors: Tural, D., Olmez, O. F., Sümbül, A. T., Artac, M., Ozhan, N., Akar, E., ... & Erman, M. (2021)

Safety and survival in adult women with platinum-sensitive relapsed BRCA mutant ovarian cancer: A study of patients in Olaparib Turkey Early Access Program—LynTurk study

• Authors: Esin, E., Ahmed, M. A., Yıldırım, H. Ç., Mandel, N. M., Erdemoglu, E., Sari, M., ... & Paydas, S. (2023)

Atezolizumab in patients with metastatic urothelial carcinoma who have progressed after first-line chemotherapy: Results of real-life experiences

• Authors: Tural, D., Ölmez, Ö. F., Sümbül, A. T., Artaç, M., Özhan, N., Akar, E., ... & Kılıçkap, S. (2021)

O Dr. Nejat Akalan é um neurocirurgião de renome, especializado em cirurgias cerebrais e de nervos, com mais de 35 anos de experiência. As suas áreas de especialização incluem epilepsia, glioma, traumatismos cranianos, distúrbios do movimento, tumores da coluna vertebral, hérnias e outros distúrbios nervosos. Ele utiliza técnicas avançadas nas suas cirurgias e publicou 117 artigos científicos e um livro.

Dr. Fritz Leutmezer is a leading neurologist and chief physician at the University Hospital of Neurology in Vienna. He also runs a private practice. He is known for his skill in diagnosing and treating neurological diseases. His main areas of focus are multiple sclerosis, epilepsy, headaches, and inflammatory disorders of the nervous system.

Dr. Leutmezer uses advanced treatment methods. He often includes acupuncture for headaches, musculoskeletal pain, nerve pain, facial paralysis, and spasticity, especially in patients with multiple sclerosis. His clinic is known for high patient satisfaction and follows the latest international standards in neurology.