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Oncosurgeon, Head of Samsung Department of Urology

Urologist, Oncosurgeon

One of the world-renowned pioneers in gastrointestinal surgery. Has developed new techniques for the colon and rectum cancer treatment TaTMEТ and NOTES — applied now around the world.
Has performed over 15,000 surgeries.
Performs over 1,000 interventions a year using minimally invasive techniques.
President of the Association of Surgeons-Endoscopists in Europe.

Radiotherapy specialist, Oncologist

Gynecologist, Specialist in endoscopic and laparoscopic operations

Head of the Breast Surgery Department, Mammologist

Head of Rambam Department of Urology, Oncosurgeon

Areas of Interests

• Genital Laser Application ( Vajinal  Rejuvenation , Laser Incontinence Treatment)
• Aesthetic  Genital  Surgery ( Labioplastia, Vaginoplastia, Perineoplastia )
• Vaginismus Treatment.
• Treatment Of Female Sexual Function Disorders.
• Hormonal & Non-Hormonal Treatment.
• Laser Incontinence Treatment.
• Medical Treatment İn Incontinence.

Education

• Hacettepe  University  Faculty of  Medicine, ANKARA.
• SBÜ. ANKARA Dr. Zekai Tahir Burak  Training and  Research  Hospital.

Experience

• SBÜ.ANKARA Dr. Zekai Tahir Burak Training and Research Hospital.
• Antalya Training and  Research  Hospital,
• Jinefem , Private Gynecology Center, ANTALYA
• SM Clinic, Private Gynecology Center, ANTALYA
• Liv Hospital Ulus, İSTANBUL

Research:

• Gestational  Diabetic  Evaluation of  Affinity in Pregnant  Woman in Turkey.
• The  Effect of Intrauterin Insemination on  Pregnancy  Rates in Infertile Woman in 456 cycles.
• The  Effect of  Genital  Laser  Applications on  Urinary  Incontinence  Treatment.
• The  Effect of  Genital  Laser  Applications  on  Vaginal  Atrofi  in  Menopause.
• Distribution of Human Papilloma Virus (HPV) İnfection in the Mediterranean Region in Turkey.

Dr. Elnur Sahibov is a licensed Radiation Oncologist with 8 years of medical training and clinical experience. He completed his undergraduate and specialization studies at Marmara University Faculty of Medicine. From 2012 to 2016, he focused on advanced radiation oncology techniques.

Dr. Sahibov is known for his expertise in cancer treatment. He has helped improve patient outcomes and uses evidence-based protocols. He is accredited by leading medical institutions and is dedicated to ongoing professional development in oncology.

Dr. Kemal Raşa is a highly experienced General Surgeon specializing in Modern Thyroidology & Laparoscopic Surgery with 23 years of experience. He is affiliated with several medical associations and has published several papers in his field.

Education

Cumhuriyet University Faculty of Medicine, 2004
Istanbul Haydarpaşa Training and Research Hospital Internal Medicine Residency, 2010
Karadeniz Technical University Faculty of Medicine Medical Oncology Residency, 2015

Experience

MD Andeson Cancer Center, USA, 2008
Sunnybrook Odette Cancer Center Breast Cancer Clinic, Canada, 2017
Moffit Cancer Center , USA 2022
Istanbul Haydarpaşa Training and Research Hospital Internal Medicine, 2010
İdil State Hospital Internal Medicine Clinic, 2011
Karadeniz Technical Universityniversitesi Faculty of Medicine, Medical Oncology Clinic, 2015
Istanbul Göztepe Training and Research Hospital, Medical Oncology Clinic, 2018
Yeniyüzyıl University Gaziosmanpaşa Hospital, Medical Oncology Clinic, 2020
Ataşehir Medicana Hospital, Medical Oncology Clinic, 2022

Scientific Membership

Turkish Medical Association (TTB)
Turkish Society of Medical Oncology (TTOD)
European Society for Medical Oncology (ESMO)
American Society of Medical Oncology (ASCO)

Medical Intrests

• Breast Cancer
• Lung Cancer
• Colon Cancer
• Stomach Cancer
• Rectal Cancer
• Ovarian Cancer
• Liver Cancer
• Oesophageal Cancer - Oesophageal Cancer
• Kidney Cancer
• Larynx Cancer - Cancer of the Larynx
• Thyroid Cancer
• Head and Neck Cancers
• Gynaecological Cancers
• Pancreatic Cancer
• Oesophageal Cancer - Oesophageal Cancer
• Uterine Cancer
• Brain Cancers - Brain Tumours
• Soft Tissue Cancer - Sarcomas
• Prostate Cancer
• Bladder Cancer
• Bile Tract Cancer
• Testicular Cancer
• Cervical Cancer
• Mouth, Tongue, Lip Cancers
• Gastrointestinal System Cancers
• Bone Tumours
• Trachea and Bronchial Cancers
• Skin Cancers - Skin Cancers
• Skeletal System Tumours
• Gallbladder Cancer
• Mesothelioma

Areas of Interests

• Breast cancer
• Lung cancer
• Colorectal cancers
• Gynecological and urogenital cancers
• Molecular Oncology

Education:

• Kızıltepe Anatolian High School 2001
• Dicle University Faculty of Medicine 2007
• Istanbul Medeniyet University Göztepe Training and Research Hospital 2014
• Kartal City Hospital 2021
• Associate Professor of Medical Oncology 2023

Experience:

• Liv Hospital Ulus
• Adıyaman University Training and Research Hospital
• Istanbul Umraniye Training and Research Hospital
• Istanbul Umraniye Training and Research Hospital

Research:

• Phase II, Randomized, Open-Label, Multicenter Study to Comparatively Evaluate the Efficacy and Safety of GDC-9545 and Physician-Preferred Endocrine Monotherapy in Previously Treated, Estrogen Receptor Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer Patients, Other ( International), Dr. Murat Ayhan
• Phase III, Randomized, Evaluating the Efficacy and Safety of Palbociclib and Fulvestrant with Gdc-0077 Compared with Placebo in Patients with Pik3ca-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer. Double Blind, Placebo Controlled Study, Other (International), Dr. Murat Ayhan
• Randomized, Multicenter, Phase Ib/III Study Evaluating the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Atezolizumab Compared to Intravenous Atezolizumab in Patients with Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer, Other (International) Dr. Murat Ayhan
• Randomized, Controlled, Multicenter, Open-Label Study Including Observation Follow-Up for PSMA-PET-Negative Patients, Investigating the Efficacy and Safety of Addition of Apalutamide to Radiotherapy and LHRH Agonist in PSMA-PET-Positive High-Risk Hormone-Sensitive Prostate Cancer Patients, Other (International) Dr. Murat Ayhan
• Biomarker Study to Identify Patients with Advanced Stage Urothelial Cancer and Fibroblast Growth Factor Receptor Gene Aberrations-42756493BLC0002, Other (International), Dr. Murat Ayhan
• Publications:
• Ayhan M, Turan N, Köstek O, et all. Does the efficacy of regorafenib differ in chemotherapy refractory metastatic colorectal cancer patients who had mucinous pathology compared to those who had non-mucinous pathology? Curr Probl Cancer. 2021 Jun;45(3):100670. doi: 10.1016/j.currproblcancer.2020.100670.
• Ayhan M, Odabas H, Turan N, et all. Factors affecting the mortality rate of patients with cancer hospitalized with COVID-19: a single center's experience. J Chemother. 2021 Nov;33(7):499-508. doi: 10.1080/1120009X.2021.1923153.
• Ayhan M, Laçin Ş, Özyükseler DT, et all. Does systemic anti-tumor therapy increase COVID-19 risk in patients with cancer? J Oncol Pharm Pract. 2021 Sep;27(6):1461-1467. doi: 10.1177/10781552211015762.
• Ayhan M, Abamor E, Coban Kokten S, et al. Value of FDG PET/CT in Predicting Pathologic Complete Response After Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer. EJMI 2022;6(2):165–175.
• Ayhan M, Terzioglu K. Experience With Rapid Drug Desensitization With Chemotherapeutics; A SingleCentre Retrospective Study. EJMI 2021;5(3):380–387.
• Doğan A, AYHAN M. Survival analysis of patients with triple-negative breast cancer: a single-center experience. Journal of Oncological Sciences, 8(2), 94-99., Doi: 10.37047/jos.2022-89749
• Terzioğlu K, Ayhan M. Comparative Assessment of Platinum Salts and Taxane Group Hypersensitivity Reactions, The Role of Skin Tests in Diagnosis? J Oncol Pharm Pract. 2021 Nov 30:10781552211050084. doi: 10.1177/10781552211050084.
• Tacar SY, Selcukbiricik F, Yilmaz M, Erturk K, Murat Sarici A, Gulturk I, Ayhan M, Tural D. Nivolumab for metastatic uveal melanoma: a multicenter, retrospective study. Melanoma Res. 2021 Oct 1;31(5):449-455. doi: 10.1097/CMR.0000000000000744.
• Özyurt E, Özçelik S, Sürmeli H, Çelik M, Ayhan M, Özçelik M. Side effects of immune-checkpoint inhibitors: Can multiple side effects be seen in a patient? J Oncol Pharm Pract. 2022 Mar;28(2):462-465. doi: 10.1177/10781552211038136.
• Dülgar Ö, Öven BB, Atcı MM, Arıkan R, Ay S, Ayhan M, Selvi O, Ozyukseler DT, Bayram E, Özcan E, Yasin Aİ, Gümüş M. Is the benefit of using adjuvant capecitabine in patients with residual triple-negative breast cancer related to pathological response to neoadjuvant chemotherapy? Expert Rev Anticancer Ther. 2022 Jul;22(7):773-780. doi: 10.1080/14737140.2022.2076670.
• Hizal M, Bilgin B, Paksoy N, Ayhan M, et all. The real-life efficacy and safety of osimertinib in pretreated advanced non-small cell lung cancer patients with T790M mutation: a Turkish Oncology Group Study. J Cancer Res Clin Oncol. 2022 Jun;148(6):1501-1508. doi: 10.1007/s00432-021-03748-7.
• Volume I, Kucukarda A, Atcı MM, Ayhan M, et all. Efficacy and safety of trastuzumab emtansine in older patients with HER2-positive advanced breast cancer: a real-world study. Tumori. 2022 Feb;108(1):19-25. doi: 10.1177/03008916211037739.
• Dogan I, Ayhan M, Gurbuz M, et all. The frequency and prognostic significance of ABO/Rh blood groups in male breast cancer patients: A multicenter study. Medicine (Baltimore). 2022 Sep 2;101(35):e30147. doi: 10.1097/MD.0000000000030147.
• Ozcelik M, Oyman A, Cil I, Duzgun O, Ozkan OF, Ayhan M. Cytoreductive Surgery versus Systemic Chemotherapy alone in Isolated Peritoneal Carcinomatosis of Colorectal Origin. J Coll Physicians Surg Pak. 2021 Nov;31(11):1308-1313. doi: 10.29271/jcpsp.2021.11.1308.
• Başoğlu T, Sakin A, Erol C, Ayhan M, et all. Real life experienceof patients with locally advanced gastric and gastroesophageal junction adenocarcinoma treated with neoadjuvant chemotherapy: a Turkish oncology group study. J Chemother. 2022 May 17:1-8. doi: 10.1080/1120009X.2022.2073159.
• Özdemir Ö, Zengel B, Yildiz Y, Ayhan M, et all. The effectiveness and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early-stage human epidermal growth factor receptor 2-positive breast cancer: Turkish Oncology Group study. Anticancer Drugs. 2022 Aug 1;33(7):663-670. doi: 10.1097/CAD.0000000000001310.
• Hizal M, Bilgin B, Paksoy N, Ayhan M, et all. The percentage of ALK-positive cells and the efficacy of first-line alectinib in advanced non-small cell lung cancer: is it a novel factor for stratification? (Turkish Oncology Group Study). J Cancer Res Clin Oncol. 2022 Sep 1. doi: 10.1007/s00432-022-04252-2.
• Hizal M, Bilgin B, Paksoy N, Ayhan M, et all. Real-world data on efficacy and safety of first-line alectinib treatment in advanced-stage, ALK-positive non-small-cell lung cancer patients: a Turkish Oncology Group study. Future Oncol. 2022 Jul;18(23):2573-2582. doi: 10.2217/fon-2022-0083.
• Topcu A, Atci MM, Secmeler S, Besiroglu M, Ayhan M, Ozkan M, Bozkurt O, Urakci Z, Ay S, Geredeli C, Yasin AI, Turk HM. Efficacy of trastuzumab and potential risk factors on survival in patients with HER2-positive metastatic gastric cancer. Future Oncol. 2021 Nov;17(31):4157-4169. doi: 10.2217/fon-2021-0398.
• Bilgin B, Sendur MAN, Yucel S, Ayhan M, et all. Real-life comparison of the afatinib and first-generation tyrosine kinase inhibitors in nonsmall cell lung cancer harboring EGFR exon 19 deletion: a Turk Oncology Group (TOG) study. J Cancer Res Clin Oncol. 2021 Jul;147(7):2145-2152. doi: 10.1007/s00432-020-03501-6.
• Atci MM, Akagunduz B, Demir M, Arikan R, Ay S, Ozer M, Ayhan M, Cil I, Demir N, Ozyurt N, Karakaya G, Cevik GT, Onder AH, Selvi O, Sakin A. The impact of adjuvant oxaliplatin and tumor sidedness on the overall survival of stage IIB colon cancer patients: a multicentre study. J Chemother. 2023 Feb;35(1):19-28. doi: 10.1080/1120009X.2022.2040770.
• Tataroglu Ozyukseler D, Ay S, Turan M, Alkan G, Ayhan M, Surmeli H, et al. The Systemic Inflammation Response Index as a Prognostic Marker in Advanced Pancreatic Cancer. EJMI 2022;6(3):367–373.
• Yıldız F, Ayhan M, Demir H, et all. Comparing the efficacy of cabazitaxel in secondline and third-Line treatment of metastatic castration-resistant prostate cancer: a multi-center experience from Turkey. International Journal of Contemporary Medical Research, 7(9), 112-116.,Doi: 10.21276/ijcmr.2020.7.9.30
• Terzioğlu K, Ayhan M. Distribution of allergens detected on patch tests of patients with allergic contact dermatitis and investigation of their atopic background. Annals of Medical Research, 29(5), 422-426., doi: 10.5455/annalsmedres.2021.07.490
• Arikan R, Atci MM, Ay S, Ayhan M, et all Prognostic significance of mucinous histology in left sided metastatic colorectal cancers with wild type RAS and evaluation of backbone chemotherapy regimens. Oncol Lett. 2023 Apr 5;25(5):208. doi: 10.3892/ol.2023.13795.
• Almuradova E, Yalcin S, Arıkan R, Ayhan M, Demir H, Cevik GT, Karaca M, Petekkaya I, Karabulut B. Survival of Patients With Metastatic Rectum Cancer Who Underwent Metastasectomy Following Conversion Chemotherapy Sans Pelvic Radiotherapy: A Turkish Oncology Group Study. Cureus 2023 May 17;15(5):e39119. doi: 10.7759/cureus.39119.
• Topcu A, Besiroglu M, Atci MM, Ayhan M, et all. Second-line Therapy after Trastuzumab Failure in HER2-Positive Metastatic Gastric Cancer: A Real-life Data. EJMI 2023;7(2):153–161. DOI: 10.14744/ejmi.2023.22720
• Book Writing:
• Drug interactions and side effects of targeted agents, Section name: (Small molecule tyrosine kinase inhibitors; ROS-1 targeted therapies (Crizotinib, Seritinib)) (2021)., AYHAN MURAT, Turkish Clinics Journal of Medical Sciences, Editor: Mehmet Aliustaoglu, Publishing number:1, Number of Pages 92, ISBN:978-625-401- 466-6, Turkish
• Approach to gastrointestinal stromal tumors and neuroendocrine tumors, Department name: (Medical approach in primary non-gastrointestinal neuroendocrine tumors) (2020)., AYHAN MURAT, Akademisyen Yayınevi, Editor: Anılır Ender, Number of editions: 1, Number of Pages 382, ISBN: 9786052585719, Turkish
• Internal medicine emergencies, Department name: (Oncological emergencies) (2022)., YILDIRIM SEDAT, AYHAN MURAT, Efe Academic Publishing, Editor: Serdar Olt, Number of editions: 1, Number of Pages 232, ISBN: 978-625-8324-66- 2, Turkish
• Physicians' chemotherapy cancer drug manual 2020, Section name: (Common chemotherapy regimens in clinical practice) (2022)., SÜMBÜL AHMET TANER, ALKAN ALI, AKSOY ASUDE, AYHAN MURAT, et all, Türkiye Klinikleri Journal of Medical Sciences, Editor: EDWAR CHU, VINCENT T. DEVITA, SAADDETIN KILIÇKAP, CEMIL BILIR, SELÇUK SEBER, Number of editions: 1, Number of pages 772, ISBN: 978-625-401-290- 7, Turkish (Book Translation)

Desde janeiro de 1993, o Dr. Totaro exerce o cargo de Coordenador do Centro de PMA (Procriação Medicamente Assistida) e do Centro de Ecografia Obstétrica-Ginecológica no Ospedale Santa Maria, no Departamento Materno-Infantil. Sob sua supervisão, o Centro, um dos principais centros de PMA na Itália, realiza mais de 1.000 procedimentos por ano. Ospedale Santa Maria - está em primeiro lugar, pelo número de ciclos de IIU, inseminação intrauterina (586) - técnica de nível I, enquanto pelo número de procedimentos de descongelamento de oócitos - técnicas de nível II e III - o hospital de Santa Maria de Bari ocupa o 4.º lugar no ranking nacional.

Em 1986, o Dr. Totaro formou-se em Medicina e Cirurgia pela Universidade de Bari, Itália, com nota máxima, onde 4 anos depois se especializou em Ginecologia e Obstetrícia. Ele então completou seu diploma com a participação em vários cursos profissionais, como "Monitorização biofísica e bioquímica do feto" (curso de um ano, 1991, Bari) e obteve um diploma em Sexologia Clínica pelo ELEUSIS – Centro Internacional para o estudo, pesquisa e terapia das disfunções sexuais femininas, masculinas e de casal (curso de dois anos, 1996, Bari).

Para ampliar seus conhecimentos no campo científico obstétrico-ginecológico, o Dr. Totaro participa, tanto como moderador e palestrante quanto como organizador, em inúmeras conferências, simpósios, congressos e cursos (mais de 40 congressos nacionais e internacionais) e é autor de mais de 30 publicações científicas.

O Dr. Totaro é membro ativo das seguintes organizações:

ESHRE (Sociedade Europeia de Reprodução Humana e Embriologia)

SIRU (Sociedade Italiana de Reprodução Humana)

SIGO (Sociedade Italiana de Ginecologia e Obstetrícia)

AOGOI (Associação Italiana de Obstetras e Ginecologistas Hospitalares)

SIMOP (Sociedade Italiana de Médicos de Hospitais Privados)

ESG (Sociedade Europeia de Ginecologia).

Education

Istanbul University Cerrahpaşa Faculty of Medicine, 2002
Istanbul Fatih Sultan Mehmet Training and Research Hospital, Internal Medicine, 2010
Istanbul University Oncology Institute (Çapa), Medical Oncology, 2015
Medipol University Faculty of Medicine, Phytotherapy Education, 2018
University of Health Sciences, Vocational School of Health, Molecular Oncology, PhD Program, PhD, 2023

Experience

University Hospital, Newark, New Jersey, USA, Observer (2003-2004)
Siirt State Hospital, Internal Medicine (2010-2011)
Siirt State Hospital, Medical Oncology (2015)
Bakırköy Dr. Sadi Konuk Training and Research Hospital, Medical Oncology (2015-2018)
Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Medical Oncology, (Professor Doctor) (2018-Present)
Forensic Medicine 3. Specialization Board, Medical Oncology, Full Member (2019-Present)
Liv Hospital, Ulus, Park-time, Medical Oncology (2020-2022)
Şişli Kolan International Hospital, Park-time, Medical Oncology (2022-2023)

Medical Intrests

• Gastrointestinal System Tumours (Esophagus - Stomach and Large Bowel Cancer)
• Hepatobiliary System Tumours (Liver-Biliary Tract and Pancreatic Cancer)
• Breast Cancer
• Lung Cancer
• Genitourinary Cancers
• Immunotherapies and Target Therapies
• Molecular Oncology
• Immunotherapies
• Target Treatments
•  

Awards

2010-YDUS (Subspecialty Examination) 14th place in Turkey
2014- Oncology Institute Days Best Poster Award
2015- Turkish Medical Oncology Society Board Exam Qualification
2015- ESMO (European Society for Medical Oncology) Board Exam Qualification

Areas of Interests

• Infertility
• In Vitro Fertilization (IVF) Treatment
• Endometriosis
• Urogynecology (urinary incontinence and uterine prolapse surgeries)
• Gynecological Laparoscopic surgeries
• Hysteroscopic surgeries
• Pregnancy Monitoring
• Myoma surgery
• Ovarian cysts and surgeries
• Gynecological plastic surgeries

Education:

• Ataturk University Faculty of Medicine - Undergraduate
• Abant Izzet Baysal University Faculty of Medicine Gynecology and Obstetrics - Specialization
• Bezmialem Vakif University Faculty of Medicine Istanbul - Assistant Professorship
• Bezmialem Vakif University Faculty of Medicine Istanbul - Associate Professorship
• American Hospital - Assisted Reproductive Specialist Training

Experience:

• Bolu Izzet Baysal State Hospital (Compulsory Service) -Bolu
• Bezmialem Vakif University Faculty of Medicine - Istanbul

Dr. Namrata Jadhav brings with her more than 14 years of experience in the field of Obstetrics and Gynaecology. She has pursued MBBS, DNB, GO, MNAMS from leading colleges and hospitals in Mumbai, India. She has obtained training in Cosmetic Gynaecology in UAE. She has also taken laparoscopic training in a year 2016 and 2022.
Dr. Namrata is proficient in High-Risk Obstetrics, hypertension/diabetes in pregnancy, recurrent abortions, previous LSCS, vaginal birth after LSCS, management of pregnancy after IV/infertility treatment, just to name a few.

She also has a passion for pre-pregnancy, pregnancy counselling to make the journey a memorable, postpartum care and weight management, and is even known for painless pap smears and examinations. Dr. Namrata is also proficient in treating recurrent UTI/vaginal infections, handling cosmetic gynaecology cases, and is an expert when it comes to POS management, PCO related issues, and abnormal bleeding in adolescence.

Dr. Jelena is a Specialist Obstetrician & Gynecologist with over 25 years of experience in her field. She began her medical studies in 1986 at the University of Belgrade Medical School, Belgrade. She completed her primary Medical Degree in 1992 and continued with her internship the following year at the Clinical Centre of Serbia while working as a General Practitioner.

Dr. Jelena has worked at the Gynecology & Obstetrics Clinic Narodni front (Belgrade, Serbia), Special Gynecology Hospital Genesis Medical (Belgrade, Serbia) and General Hospital ST MEDICA (Belgrade, Serbia).

She also worked for two years as a Professor in Gynaecology & Obstetrics for students of the High Medical School, Belgrade, Serbia. She held a post as a Consultant in Gynaecology & Obstetrics for several private clinics in Belgrade.
In April 2016, she moved to Dubai where she started to work as Gynaecology & Obstetrics Specialist.

She specialises in Gynaecological and Obstetrical Ultrasound (4D ultrasound), Gynaecology Endocrinology, Lower Genital Tract Pathology, Hysteroscopy, Prenatal and Post-natal care, Antiaging Treatment, Laser Treatment for Stress Urinary Inconsistency and Vaginal Relaxation Syndrome, Laser Vaginal Tightening, Laser Vaginal Rejuvenation/Vaginal Atrophy Laser Treatment, Invasive and Non-Invasive Gynaecological Diagnosis (HSSG, SIS, HSG) & Aesthetic Gynaecology.