Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) for Pediatric Hodgkin Lymphoma (HL) at Sheba Hospital- JCI accredited and Top-10 Hospitals 2026 by Newsweek

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Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation)for Pediatric Hodgkin Lymphoma (HL)

Sheba Medical Center – Advanced, Personalized Transplant Care for Children

At Sheba Medical Center, we understand that a diagnosis of Hodgkin Lymphoma (HL) in a child or adolescent is a deeply emotional experience for the entire family.

While many children with Hodgkin Lymphoma respond successfully to standard treatments such as chemotherapy and radiotherapy, some cases require more advanced therapy. For children with relapsed, refractory, or high-risk disease, Autologous Stem Cell Transplantation (ASCT) is a highly effective and well-established treatment approach that can help achieve long-term remission.

Our pediatric transplant program combines global expertise, advanced medical technology, and compassionate, family-centered care to support children and families throughout every stage of treatment and recovery.

The Role of Autologous Stem Cell Transplantation in Pediatric Hodgkin Lymphoma

Autologous Stem Cell Transplantation uses the child’s own healthy stem cells to restore bone marrow function after intensive chemotherapy.

This approach plays a central role in treating:

Relapsed Hodgkin Lymphoma

When Hodgkin Lymphoma returns after initial treatment, ASCT may help achieve deeper disease control and improve long-term outcomes.

Refractory Disease

For children whose lymphoma does not respond adequately to standard therapy, high-dose chemotherapy followed by stem cell rescue offers a more intensive and effective treatment strategy.

High-Risk Disease

In selected high-risk cases, ASCT may be recommended as consolidation therapy to strengthen treatment response and reduce the risk of recurrence.

How the Treatment Works

Stem Cell Collection

Before high-dose chemotherapy begins, healthy stem cells are collected from the child’s bloodstream and safely preserved.

High-Dose Chemotherapy

Children then receive intensive chemotherapy designed to eliminate remaining lymphoma cells throughout the body.

Stem Cell Rescue

After chemotherapy, the child’s own stem cells are reinfused to restore bone marrow function and support immune system recovery.

This process allows doctors to deliver highly effective treatment while helping the body rebuild healthy blood-forming cells.

Donor Options – Always a Solution Available

Although most children with Hodgkin Lymphoma undergo autologous transplantation using their own stem cells, some complex cases may require an allogeneic (donor) transplant.

If a donor-based approach is needed, Sheba Medical Center provides access to multiple donor options:

Matched family donors, when available
Matched unrelated donors through international registries
Haploidentical (half-matched) family donors
Cord blood transplantation

Using advanced matching technologies and global donor access, our team works to ensure that every child can receive the most suitable transplant option, even when a family match is not available.

Advanced Pediatric Transplant Care

Children undergoing transplantation at Sheba are treated in dedicated pediatric transplant units designed specifically for young patients and their families.

Care includes:

Highly protected, child-friendly environments
Advanced infection prevention systems
Pediatric-specific chemotherapy and transplant protocols
Continuous monitoring by experienced pediatric oncology and transplant teams

Every aspect of care is adapted to the physical and emotional needs of children.

Precision, Safety, and Support

Sheba Medical Center utilizes advanced laboratory technology and highly specialized transplant protocols to optimize safety and treatment effectiveness.

Our multidisciplinary teams provide comprehensive supportive care throughout every stage of transplantation and recovery.

Clinical Expertise in Pediatric Hodgkin Lymphoma

Sheba Medical Center is a leading center for pediatric hematologic malignancies, offering:

Extensive experience in relapsed and refractory Hodgkin Lymphoma
Expertise in Autologous Stem Cell Transplantation
High success rates with advanced transplant protocols
Long-term follow-up focused on growth, development, and quality of life

Our treatment strategies are continuously refined according to the latest international research and clinical advances.

Care That Supports the Whole Family

We recognize that treating a child means supporting the entire family.

At Sheba, families are cared for by a multidisciplinary pediatric team including oncologists, transplant specialists, nurses, psychologists, social workers, and care coordinators.

From diagnosis through recovery, families receive clear communication, emotional support, and continuous guidance every step of the way.

Why Families Choose Sheba for Pediatric ASCT
Leading center for pediatric transplantation in lymphoma

Strong expertise in relapsed and refractory Hodgkin Lymphoma
Advanced autologous transplant protocols
Ability to secure suitable donors when needed
Safe, supportive, child-centered care environment
Dedicated international patient coordination services

A Message of Hope

At Sheba Medical Center, we combine advanced medical science with compassionate pediatric care. Through innovative approaches like Autologous Stem Cell Transplantation, we strive to provide children with Hodgkin Lymphoma the strongest possible chance for recovery, while supporting families with confidence, care, and hope throughout the entire journey.

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