Sheba Pediatric Personalized CAR-T Immunotherapy Program for Blood Cancers at JCI accredited and Top-10 Hospitals 2026 by Newsweek Hospital
O que está incluído neste pacote
Procedimentos médicos
- Terapia com células T CAR
- 3 refeições por dia pelo nutricionista
- Serviços de enfermagem 24 horas
- Tomografia Computadorizada
- Eletrocardiograma (ECG)
- Exames de sangue
- Radiografia do tórax
- Teste anti-HIV
- Teste anti-HBC
- Teste Anti-HCVAb
- Ecocardiografia
- Hemograma completo (HC)
- Exame de sangue para bioquímica
- Consulta com um oncologista
- Consulta com um hematologista
- Consulta com um hematologista pediátrico
- Consulta com um pediatra
- Consulta com um onco-hematologista
- Ressonância Magnética do Crânio
- Biópsia
- Hemograma completo com marcadores tumorais e proteinograma
Duração
- 21 dias no hospital
Acomodação
Hospitalização
Transporte
Transfer aeroporto-hotel-aeroporto
Informações adicionais
Sheba Pediatric Personalized CAR-T Immunotherapy Program for Blood Cancers
At Sheba Medical Center, children and young patients receive some of the most advanced and compassionate cancer care available today. Sheba is a global leader in pediatric CAR-T cell therapy, offering highly personalized treatment for complex and resistant blood cancers, including:
• Acute lymphoblastic leukemia (ALL) and Acute Myeloid Leukemia (AML)
• Non-Hodgkin lymphomas (DLBCL, FL, MCL)
• Burkitt lymphoma
• CLL / Richter’s transformation
• Primary CNS lymphoma
• Multiple myeloma
A Gentle, Fully Integrated CAR-T Journey
Every step of the CAR-T process is performed on-site at Sheba, ensuring speed, safety, and the highest quality of care, especially important for children.
The treatment includes three carefully coordinated stages:
• Apheresis – collecting the child’s own immune (T) cells
• Cell Engineering – reprogramming the cells at Sheba’s Advanced Biotherapy Center
• Infusion – returning the cells to fight the cancer
Because everything is done within the hospital, treatment can begin quickly and is typically completed within ~10 days. CAR-T works as a “living therapy,” continuing to act in the body and offering the potential for long-term remission.
All patients are treated under the guidance of leading experts, including Prof. Amos Toren, with dedicated pediatric CAR-T teams ensuring continuous monitoring and care.
Designed Especially for Children and Families
Sheba understands that treating a child means caring for the entire family. The pediatric program offers:
• Specialized pediatric CAR-T units with 24/7 expert monitoring
• A multidisciplinary team of hemato-oncologists, immunologists, and pediatric specialists
• A supportive, child-friendly environment focused on comfort and safety
• Full international patient support, including travel and care coordination
Clinical Excellence You Can Trust
Sheba is one of the world’s leading centers in pediatric CAR-T, with strong clinical outcomes:
• ~90% remission in pediatric patients
• ~80% in young adults (up to 23 years)
• ~70% in adults
Importantly, Sheba offers flexibility in age criteria, ensuring that children and young patients can access advanced therapies when needed.
Comprehensive Care from Start to Finish
Each child receives a complete evaluation before treatment, including:
advanced imaging, bone marrow testing, genetic and molecular analysis, and full cardiac and pulmonary assessment.
Care is provided in English, Russian, and Arabic, helping families feel supported and informed throughout the entire journey.
Why Families Choose Sheba
By combining advanced science, speed, and deeply personalized care, Sheba provides one of the most trusted pediatric CAR-T programs in the world focused not only on treating disease, but on giving children the best possible chance to return to a healthy, active life.
Assistência Bookimed 24/7
- Coordenador médico pessoal
- Arranjos de viagem médica — reserva de passagens aéreas e quartos de hotel com preços especiais de parceiros
- Defesa do paciente durante a viagem médica
Preço do programa
O que NÃO está incluído neste pacote
Médico
Prof. Amos Toren, MD, PhD, MHA, is a pediatric hemato-oncologist and BMT specialist. He served as Director of Pediatric Hemato-Oncology and BMT at Sheba Medical Center.
He is board certified in Pediatrics, Pediatric Hemato-Oncology, and Bone Marrow Transplantation. He holds a PhD in Human Genetics. He was Head of the Hematology Division at Tel Aviv University for two terms. He is a member of ASH, COG, ESPHI, EBMT, and CIBMTR. He also serves on the Ministry of Health Cord Blood Committee.
He led one of Israel’s most advanced pediatric oncology and BMT programs. The program treated children and young adults. His focus includes leukemia and lymphoma, immunodeficiencies, and rare cancers. He specializes in BMT and CAR T-cell therapy.
His translational research covers CAR T cells, cytokine-induced killer cells, pediatric brain tumors, and targeted therapies. He has worked with St. Anna, the NIH, and St. Jude. His publications include studies on pediatric SCT prophylaxis and PARP resistance.
Como estamos indo?
Sobre a clínica
A terapia com células CAR-T no Sheba Medical Center em Tel Aviv, Israel, pode custar cerca de US$ 63.100 pelo programa completo. O hospital está entre os 10 melhores do mundo e oferece este tratamento avançado sob a coordenação do Prof. Arnon Nagler, um renomado especialista em transplante de medula óssea.
Sobre o Tratamento
A terapia com células CAR-T é uma abordagem inovadora para leucemia, linfoma e mieloma múltiplo. O processo envolve a coleta das células T do paciente, sua modificação genética em laboratório e a reinfusão após a quimioterapia. O procedimento exige 21 dias de internação hospitalar, com possibilidade de permanência na UTI.
O que está incluído
- Avaliação abrangente (US$ 5.000 - US$ 10.000)
- Coleta de células via aférese (US$ 6.600)
- Preparação laboratorial das células modificadas (US$ 20.000)
- Quimioterapia de condicionamento (US$ 5.000)
- Internação de 21 dias (US$ 31.500)
- Avaliação pós-tratamento (US$ 3.000 - US$ 5.000)
Preparação e Recuperação
Os pacientes necessitam de biópsia de medula óssea, exames de PET/CT e exames de sangue antes do tratamento. Após a infusão, ocorre o monitoramento diário para a síndrome de liberação de citocinas. A permanência total recomendada em Israel é de 4 a 6 semanas. Vale ressaltar que o CAR-T para mieloma ainda é experimental.
O Sheba Medical Center atende 1,5 milhão de pacientes anualmente e oferece atendimento multilíngue. É necessário um depósito de US$ 50.000 a US$ 60.000 antes da chegada. Entre em contato com o hospital para avaliar se esta terapia é adequada para o seu caso.
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